Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.88 |
| ▸ | CTSK | P43235 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19186938 | 0.94 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL14822287 | 0.94 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL14822157 | 0.90 | CTSC (1.00) | CTSC | |
| SCHEMBL19187250 | 0.90 | CTSC (1.00) | CTSC | |
| SCHEMBL19187743 | 0.89 | CTSC (1.00) | CTSC | |
| SCHEMBL14822374 | 0.89 | CTSC (1.00) | CTSC | |
| SCHEMBL15064760 | 0.89 | CTSC (1.00) | CTSC | |
| SCHEMBL16064545 | 0.87 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL22643499 | 0.87 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL14822269 | 0.87 | CTSC (1.00) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665717-A2 | USES OF CERTAIN 1,4-OXAZEPANE-2-CARBOXAMIDES AS DPP1 INHIBITORS | Insmed Incorporated (US) | 2025-12-24 | — | — | EP | disclosed |
| US-20250361226-A1 | PHARMACEUTICALLY ACCEPTABLE SALT OF BENZO[C]CHROMAN COMPOUND AND POLYMORPHIC FORM AND USE OF PHARMACEUTICALLY ACCEPTABLE SALT | REISTONE BIOPHARMA COMPANY LTD (CN) | 2025-11-27 | — | — | US | disclosed |
| US-20250353839-A1 | POLYMORPH OF BENZO[C]CHROMAN COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | REISTONE BIOPHARMA COMPANY LTD (CN) | 2025-11-20 | — | — | US | disclosed |
| US-12365673-B2 | Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof | HAISCO PHARMACEUTICALS PTE. LTD. (SG) | 2025-07-22 | — | — | US | disclosed |
| EP-4538277-A1 | PHARMACEUTICALLY ACCEPTABLE SALT OF BENZO[C]CHROMAN COMPOUND AND POLYMORPHIC FORM AND USE OF PHARMACEUTICALLY ACCEPTABLE SALT | Reistone Biopharma Company Limited (CN) | 2025-04-16 | — | — | EP | disclosed |
| EP-4538271-A1 | POLYMORPH OF BENZO[C]CHROMAN COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Reistone Biopharma Company Limited (CN) | 2025-04-16 | — | — | EP | disclosed |
| EP-4497473-A2 | NITRILE DERIVATIVE THAT ACTS AS INHIBITOR OF DIPEPTIDYL PEPTIDASE 1 AND USE THEREOF | Haisco Pharmaceuticals Pte. Ltd. (SG) | 2025-01-29 | — | — | EP | disclosed |
| EP-3744714-B1 | (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE I INHIBITORS | ASTRAZENECA AB (SE) | 2025-01-15 | — | — | EP | disclosed |
| CN-119156391-A | Pharmaceutically acceptable salts of benzo [ c ] chroman compounds, polymorphs and uses thereof | 瑞石生物医药有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-119156384-A | Polymorphic forms of benzo [ c ] chroman compounds, methods of making and uses thereof | 瑞石生物医药有限公司 | 2024-12-17 | — | — | CN | disclosed |
| US-20140275025-A1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
| EP-2758398-A1 | SUBSTITUTED N- [1-CYANO-2- (PHENYL) ETHYL]-2-AZABICYCLO [2.2.1]HEPTANE-3-CARBOXAMIDE INHIBITORS OF CATHEPSIN C | Boehringer Ingelheim International GmbH (DE) | 2014-07-30 | — | — | EP | disclosed |
| EP-2758398-A1 | SUBSTITUTED N- [1-CYANO-2- (PHENYL) ETHYL]-2-AZABICYCLO [2.2.1]HEPTANE-3-CARBOXAMIDE INHIBITORS OF CATHEPSIN C | Boehringer Ingelheim International GmbH (DE) | 2014-07-30 | — | — | EP | disclosed |
| EP-2758398-A1 | SUBSTITUTED N- [1-CYANO-2- (PHENYL) ETHYL]-2-AZABICYCLO [2.2.1]HEPTANE-3-CARBOXAMIDE INHIBITORS OF CATHEPSIN C | Boehringer Ingelheim International GmbH (DE) | 2014-07-30 | — | — | EP | disclosed |
| CN-103814028-A | Cathepsin C inhibitor substituted N- [ 1-cyano-2- (phenyl) ethyl ] -2-azabicyclo [2.2.1] heptane-3-carboxamides | BOEHRINGER INGELHEIM INT | 2014-05-21 | — | — | CN | disclosed |
| US-20130172327-A1 | SUBSTITUTED N- [1-CYANO-2- (PHENYL) ETHYL] -2-AZABICYCLO [2.2.1] HEPTANE-3-CARBOXAMIDE INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-04 | — | — | US | disclosed |
| US-20130172327-A1 | SUBSTITUTED N- [1-CYANO-2- (PHENYL) ETHYL] -2-AZABICYCLO [2.2.1] HEPTANE-3-CARBOXAMIDE INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-04 | — | — | US | disclosed |
| WO-2013041497-A1 | SUBSTITUTED N- [1-CYANO-2- (PHENYL) ETHYL] -2-AZABICYCLO [2.2.1] HEPTANE-3-CARBOXAMIDE INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013041497-A1 | SUBSTITUTED N- [1-CYANO-2- (PHENYL) ETHYL] -2-AZABICYCLO [2.2.1] HEPTANE-3-CARBOXAMIDE INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013041497-A1 | SUBSTITUTED N- [1-CYANO-2- (PHENYL) ETHYL] -2-AZABICYCLO [2.2.1] HEPTANE-3-CARBOXAMIDE INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275025-A1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | CTSC, CTSB, CTSG | CTSC 1/4885CTSK 13/4885 |
| US-12365673-B2 | Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof | DPP4, DPP3, DPP9 | CTSC 4/4885CTSK 454/4885 |
| US-20250353839-A1 | POLYMORPH OF BENZO[C]CHROMAN COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | CELA1, SERPINE1, SERPINB1 | CTSC 20/4885CTSK 26/4885 |
| US-20130172327-A1 | SUBSTITUTED N- [1-CYANO-2- (PHENYL) ETHYL] -2-AZABICYCLO [2.2.1] HEPTANE-3-CARBOXAMIDE INHIBITORS OF CATHEPSIN C | CTSS, CTSB, CTSG | CTSC 9/4885CTSK 13/4885 |
| US-20250361226-A1 | PHARMACEUTICALLY ACCEPTABLE SALT OF BENZO[C]CHROMAN COMPOUND AND POLYMORPHIC FORM AND USE OF PHARMACEUTICALLY ACCEPTABLE SALT | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CS, CTRC | CTSC 8/4885CTSK 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.