Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347907 | 0.76 | — | — | |
| SCHEMBL16081522 | 0.74 | TPSAB1 (0.44) | TPSAB1CA1CA2TSHRITGB3 | |
| SCHEMBL6411473 | 0.74 | NOS3 (0.47) | NOS3NOS1NOS2 | |
| SCHEMBL2402745 | 0.74 | ALOX15 (0.46) | TPSAB1TSHRITGB3ITGA2BFAAH | |
| SCHEMBL9507721 | 0.74 | DNM1 (0.67) | DNM1TSHRFAAHCASP2NAAA | |
| SCHEMBL6935589 | 0.73 | NOS3 (0.46) | NOS3NOS1NOS2TSHR | |
| SCHEMBL9504639 | 0.72 | DNM1 (0.60) | DNM1TSHRFAAHCASP2KDM4A | |
| SCHEMBL9504658 | 0.72 | DNM1 (0.70) | DNM1TSHRFAAHCASP2NAAA | |
| SCHEMBL8121890 | 0.72 | DNM1 (0.59) | DNM1TSHRFAAHCASP2KDM4A | |
| SCHEMBL11808168 | 0.72 | NCOR2 (0.61) | CA1CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758411-A2 | MODIFIED CREATINE COMPOUNDS | Gencia Corporation (US) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013043580-A2 | MODIFIED CREATINE COMPOUNDS | GENCIA CORPORATION (US) | 2013-03-28 | — | — | WO | disclosed |