Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536505 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL291142 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL7793286 | 0.86 | TRPA1 (0.52) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL584338 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL6139335 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL23187810 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL906649 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL1617999 | 0.82 | TRPA1 (0.52) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL6137743 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| Glycerin SCHEMBL722939 | 0.80 | LMNA (0.50) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077309-A1 | HUMECTANT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-03-31 | — | — | US | disclosed |
| EP-1946743-A2 | Humectant Composition | Takasago International Corporation (JP) | 2008-07-23 | — | — | EP | disclosed |
| US-20080171794-A1 | HUMECTANT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077309-A1 | HUMECTANT COMPOSITION | HSPH1, HOGA1, HMOX2 | ALDH1A1 124/4885KDM4E 383/4885APOBEC3A 3201/4885 |
| US-20080171794-A1 | HUMECTANT COMPOSITION | HSPH1, HOGA1, HMOX2 | ALDH1A1 124/4885KDM4E 383/4885APOBEC3A 3201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.