Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536505 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL291142 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL1481096 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL7793286 | 0.83 | TRPA1 (0.52) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL4582679 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL1617999 | 0.80 | TRPA1 (0.52) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL18473587 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL5162887 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL1401242 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL22130836 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KDM4EAPOBEC3AAPOBEC3GLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494104-B1 | WARMING SENSATION COMPOUNDS | TAKASAGO PERFUMERY CO LTD (JP) | 2023-11-15 | — | — | EP | claimed |
| EP-3658109-B1 | COOLING AND FLAVOR BOOSTING COMPOSITIONS | FIRMENICH & CIE (CH) | 2022-12-07 | — | — | EP | claimed |
| US-11059771-B2 | Warming sensation compounds | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2021-07-13 | — | — | US | claimed |
| US-11034644-B2 | — | — | 2021-06-15 | — | — | US | claimed |
| US-20200306156-A1 | COOLING AND FLAVOR BOOSTING COMPOSITIONS | FIRMENICH SA (CH) | 2020-10-01 | — | — | US | claimed |
| US-20190169111-A1 | WARMING SENSATION COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2019-06-06 | — | — | US | claimed |
| EP-2810564-B1 | Sensation masking composition | TAKASAGO INT CORP (USA) (US) | 2017-06-14 | — | — | EP | claimed |
| US-20150327583-A1 | SENSATION MASKING COMPOSITION | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2015-11-19 | — | — | US | claimed |
| US-20140219931-A1 | P-MENTHANE-3,8-DIOL ISOMER MIXTURE, COOLING SENSATION COMPOSITION COMPRISING THE SAME, AND PRODUCT COMPRISING THE COOLING SENSATION COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-08-07 | — | — | US | claimed |
| EP-1912516-B1 | SENSATION MASKING COMPOSITION | TAKASAGO INTERNAT CORP USA (US) | 2014-06-25 | — | — | EP | claimed |
| US-20100093869-A1 | SENSATION MASKING COMPOSITION | TAKASAGO INTERNATIONAL CORP. (USA) | 2010-04-15 | — | — | US | claimed |
| US-20090275669-A1 | Flavor and fragrance composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-11-05 | — | — | US | claimed |
| US-20090035364-A1 | PARA-SUBSTITUTED 2-ALKOXYPHENOL COMPOUNDS | GIVAUDAN SA (CH) | 2009-02-05 | — | — | US | claimed |
| US-20080311232-A1 | Cooling Compounds | GIVAUDAN, SA (CH) | 2008-12-18 | — | — | US | claimed |
| EP-1912516-A2 | SENSATION MASKING COMPOSITION | Takasago International Corporation (USA) (US) | 2008-04-23 | — | — | EP | claimed |
| US-20070225378-A1 | Menthol Dearivative and Cooling Agent Composition Comprising the Same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-09-27 | — | — | US | claimed |
| US-20070092623-A1 | Food products containing a fruit component | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-04-26 | — | — | US | claimed |
| WO-2007022056-A2 | SENSATION MASKING COMPOSITION | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2007-02-22 | — | — | WO | claimed |
| US-20070036733-A1 | Sensation masking composition | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2007-02-15 | — | — | US | claimed |
| US-20060269500-A1 | Topical warming composition | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2006-11-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070036733-A1 | Sensation masking composition | TRPA1, TRPV1, TRPM5 | ALDH1A1 765/4885KDM4E 3225/4885APOBEC3A 4688/4885 |
| US-20100093869-A1 | SENSATION MASKING COMPOSITION | TRPA1, TRPV1, TRPM5 | ALDH1A1 765/4885KDM4E 3225/4885APOBEC3A 4688/4885 |
| US-20060269500-A1 | Topical warming composition | CUTA, NACA, LSM14A | ALDH1A1 4243/4885KDM4E 2963/4885APOBEC3A 2306/4885 |
| US-11059771-B2 | Warming sensation compounds | TRPA1, TRPV1, TRPV4 | ALDH1A1 1286/4885KDM4E 4002/4885APOBEC3A 4596/4885 |
| US-20200306156-A1 | COOLING AND FLAVOR BOOSTING COMPOSITIONS | TAS2R20, TAS2R10, TAS2R40 | ALDH1A1 1722/4885KDM4E 3921/4885APOBEC3A 1027/4885 |
| US-20150327583-A1 | SENSATION MASKING COMPOSITION | TRPA1, TRPV1, TRPM5 | ALDH1A1 765/4885KDM4E 3225/4885APOBEC3A 4688/4885 |
| US-20080311232-A1 | Cooling Compounds | MAL2, NCOR2, NCOA2 | ALDH1A1 2477/4885KDM4E 1580/4885APOBEC3A 4093/4885 |
| US-11034644-B2 | — | TRPA1, TRPV1, TRPV5 | ALDH1A1 593/4885KDM4E 3702/4885APOBEC3A 4589/4885 |
| US-20140219931-A1 | P-MENTHANE-3,8-DIOL ISOMER MIXTURE, COOLING SENSATION COMPOSITION COMPRISING THE SAME, AND PRODUCT COMPRISING THE COOLING SENSATION COMPOSITION | TRPM8, TAS2R8, TRPM7 | ALDH1A1 659/4885KDM4E 1928/4885APOBEC3A 3860/4885 |
| US-20070225378-A1 | Menthol Dearivative and Cooling Agent Composition Comprising the Same | TRPM7, TRPA1, TRPM2 | ALDH1A1 443/4885KDM4E 614/4885APOBEC3A 2485/4885 |
| US-20190169111-A1 | WARMING SENSATION COMPOUNDS | TRPA1, TRPV1, TRPV4 | ALDH1A1 1286/4885KDM4E 4002/4885APOBEC3A 4596/4885 |
| US-20090275669-A1 | Flavor and fragrance composition | TAS2R40, TAS2R1, TAS2R50 | ALDH1A1 77/4885KDM4E 505/4885APOBEC3A 4521/4885 |
| US-20090035364-A1 | PARA-SUBSTITUTED 2-ALKOXYPHENOL COMPOUNDS | EBP, CYP1A1, CYP2E1 | ALDH1A1 214/4885KDM4E 225/4885APOBEC3A 4131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.