Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14818397 | 0.74 | DHFR (0.41) | HTR2ADHFRLMNAFFAR4KMT2A | |
| SCHEMBL28496894 | 0.72 | KMT2A (0.39) | HTR2ADHFRLMNAKMT2A | |
| SCHEMBL28493074 | 0.70 | DHFR (0.40) | HTR2ADHFRLMNAKMT2A | |
| SCHEMBL4049990 | 0.70 | LMNA (0.45) | LMNAKMT2A | |
| SCHEMBL4753309 | 0.69 | NPC1 (0.37) | HTR2ADHFRLMNAFFAR4KMT2A | |
| SCHEMBL4750906 | 0.68 | HTR2A (0.40) | HTR2ADHFRLMNAKMT2A | |
| SCHEMBL4754289 | 0.68 | FFAR4 (0.39) | HTR2ADHFRLMNAFFAR4KMT2A | |
| SCHEMBL9052736 | 0.68 | FFAR4 (0.42) | HTR2AFFAR4KMT2A | |
| SCHEMBL28978441 | 0.67 | DHFR (0.40) | HTR2ADHFRLMNAKMT2A | |
| SCHEMBL4753363 | 0.66 | HTR2A (0.38) | HTR2ADHFRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367793-B1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | METABOLEX INC (US) | 2013-03-27 | — | — | EP | disclosed |