Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055266 | 0.78 | SIRT6 (0.44) | FFAR4MAPTGAAHTTALDH1A1 | |
| SCHEMBL9048470 | 0.76 | HTR1A (0.53) | MAPTMAPK1ADRA2CPOLBHTR1A | |
| SCHEMBL24328562 | 0.73 | KDM4E (0.49) | KDM4EMAPTGAAPTK2BMAPK1 | |
| SCHEMBL29661478 | 0.73 | KDM4E (0.49) | KDM4EMAPTGAAPTK2BMAPK1 | |
| SCHEMBL6972009 | 0.73 | DRD2 (0.44) | KDM4EMAPTGAAPTK2BMAPK1 | |
| SCHEMBL31051911 | 0.70 | DRD2 (0.48) | KDM4EMAPTGAAPTK2BMAPK1 | |
| SCHEMBL28496894 | 0.69 | KMT2A (0.39) | KDM4EMAPTGAAALDH1A1KMT2A | |
| SCHEMBL14818397 | 0.68 | DHFR (0.41) | FFAR4KMT2AHTR2A | |
| SCHEMBL14818320 | 0.68 | HTR2A (0.36) | FFAR4KMT2AHTR2A | |
| SCHEMBL28493074 | 0.67 | DHFR (0.40) | KDM4EMAPTGAAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724580-A1 | BENZANILIDE DERIVATIVES AS 5HT-1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011243-A1 | BENZANILIDE DERIVATIVES AS 5HT-1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-04-27 | — | — | WO | disclosed |