Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KAT7 | O95251 | 3/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.36 |
| ▸ | KAT6B | Q8WYB5 | 2/20 | 0.36 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042308 | 0.81 | KDM4E (0.46) | P2RX7BRD4HTTGAAMAPT | |
| SCHEMBL14822759 | 0.81 | RIPK1 (0.44) | CYP3A4BRD4HTTGAAMAPT | |
| SCHEMBL14822757 | 0.78 | CYP3A4 (0.48) | CYP3A4BRD4HTTGAAMAPT | |
| SCHEMBL28839857 | 0.77 | HTT (0.46) | CYP3A4HTTGAAMAPTKAT7 | |
| SCHEMBL5299707 | 0.76 | BRD4 (0.43) | CYP3A4BRD4HTTGAAMAPT | |
| SCHEMBL3806937 | 0.76 | SMN1; SMN2 (0.48) | P2RX7BRD4HTTGAAMAPT | |
| SCHEMBL3440024 | 0.75 | L3MBTL1 (0.54) | P2RX7SCD5NTRK1CHRM5IDO1 | |
| SCHEMBL21523604 | 0.74 | MAPT (0.55) | P2RX7SCD5NTRK1CHRM5MAPT | |
| SCHEMBL3693605 | 0.72 | P2RX7 (0.38) | P2RX7SCD5NTRK1CHRM5DHFR | |
| SCHEMBL28845079 | 0.72 | CA12 (0.49) | HTTGAAMAPTKAT7KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410269-B2 | Phosphorescent iridium complex with non-conjugated cyclometalated ligands, synthetic method of preparing the same and phosphorescent organic light emitting diode thereof | NATIONAL TSING HUA UNIVERSITY (TW) | 2013-04-02 | — | — | US | disclosed |
| US-20110313162-A1 | PHOSPHORESCENT IRIDIUM COMPLEX WITH NON-CONJUGATED CYCLOMETALATED LIGANDS, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-22 | — | — | US | disclosed |
| US-20110313161-A1 | PHOSPHORESCENT IRIDIUM COMPLEX WITH NON-CONJUGATED CYCLOMETALATED LIGANDS, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110313161-A1 | PHOSPHORESCENT IRIDIUM COMPLEX WITH NON-CONJUGATED CYCLOMETALATED LIGANDS, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF | LIG3, LIG4, LIG1 | CYP3A4 4333/4885P2RX7 3109/4885SCD5 2403/4885 |
| US-20110313162-A1 | PHOSPHORESCENT IRIDIUM COMPLEX WITH NON-CONJUGATED CYCLOMETALATED LIGANDS, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF | LIG3, LIG4, LIG1 | CYP3A4 4333/4885P2RX7 3109/4885SCD5 2403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.