Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19886496 | 0.82 | TUBB1 (0.35) | CA1CA2 | |
| SCHEMBL10015010 | 0.82 | — | — | |
| SCHEMBL19412417 | 0.81 | HDAC1 (0.36) | — | |
| SCHEMBL17806151 | 0.80 | MAOB (0.43) | MAOB | |
| SCHEMBL25174870 | 0.80 | TRPV4 (0.32) | — | |
| SCHEMBL177480 | 0.79 | CES2 (0.35) | CES2CES1 | |
| SCHEMBL3439551 | 0.77 | CA12 (0.39) | CES2CES1CA1 | |
| SCHEMBL14551855 | 0.76 | MAOB (0.40) | CES2CES1MAOB | |
| SCHEMBL25174423 | 0.76 | TRPV4 (0.47) | — | |
| SCHEMBL28031630 | 0.75 | CA1 (0.34) | CES2CES1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040999-B2 | Liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2018-08-07 | — | — | US | disclosed |
| US-20180051021-A1 | BICYCLIC KETONE SULFONAMIDE COMPOUNDS | AMGEN INC. (US) | 2018-02-22 | — | — | US | disclosed |
| US-20170362505-A1 | COMPOUNDS HAVING A C-C TRIPLE BOND | MERCK PATENT GMBH (DE) | 2017-12-21 | — | — | US | disclosed |
| US-9777217-B2 | Compounds having a C—C triple bond | MERCK PATENT GMBH (DE) | 2017-10-03 | — | — | US | disclosed |
| US-20170210992-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2017-07-27 | — | — | US | disclosed |
| US-9657230-B2 | Alkenyl dioxane compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-9611429-B2 | Liquid crystal medium, optical device and liquid crystal compound | JNC CORPORATION (JP) | 2017-04-04 | — | — | US | disclosed |
| US-9527870-B2 | Liquid crystal compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2016-12-27 | — | — | US | disclosed |
| US-20160280996-A1 | ALKENYL DIOXANE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-09-29 | — | — | US | disclosed |
| US-20160122648-A1 | LIQUID CRYSTAL MEDIUM, OPTICAL DEVICE AND LIQUID CRYSTAL COMPOUND | JNC CORPORATION (JP) | 2016-05-05 | — | — | US | disclosed |
| US-20150368272-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2015-12-24 | — | — | US | disclosed |
| US-9181484-B2 | Compound having 2-fluorophenyloxymethane structure | DIC CORPORATION (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150087847-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| US-8916718-B2 | Compound having 2-fluorophenyloxymethane structure | DIC CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| US-20140275577-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
| US-8586803-B2 | Chlorofluorobenzene compound, optically isotropic liquid crystal medium and optical device | JNC CORPORATION (JP) | 2013-11-19 | — | — | US | disclosed |
| US-20130085306-A1 | CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | HASEBA YASUHIRO (JP) | 2013-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280996-A1 | ALKENYL DIOXANE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | YBX1, PIEZO1, HAX1 | CES2 1742/4885CES1 949/4885CA1 444/4885 |
| US-20140275577-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | PIK3CD, TEC, PIK3C3 | CES2 1522/4885CES1 3100/4885CA1 1789/4885 |
| US-20130085306-A1 | CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | DDT, BRAF, CFAP410 | CES2 1734/4885CES1 3484/4885CA1 387/4885 |
| US-20170362505-A1 | COMPOUNDS HAVING A C-C TRIPLE BOND | CCNC, AURKC, MCM3 | CES2 3250/4885CES1 4625/4885CA1 165/4885 |
| US-20180051021-A1 | BICYCLIC KETONE SULFONAMIDE COMPOUNDS | TRPV1, TRPA1, KCNJ11 | CES2 1097/4885CES1 477/4885CA1 1692/4885 |
| US-20150368272-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | YBX3, OCIAD1, PIEZO1 | CES2 2028/4885CES1 1405/4885CA1 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.