SCHEMBL14830331

SCHEMBL14830331

Cc1cc(C[C@@H](CCl)OC(=O)Oc2ccccc2)c(C)[nH]1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
USP2 O75604 1/20 0.32
KMT2A Q03164 3/20 0.31
LMNA P02545 2/20 0.31
MITF O75030 1/20 0.31
ALDH1A1 P00352 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
NSD2 O96028 1/20 0.31
POLB P06746 2/20 0.31
TSHR P16473 1/20 0.30
MEN1 O00255 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
PPARG P37231 1/20 0.30
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14830783 0.79 AR (0.34)
SCHEMBL14830582 0.72 ALOX15 (0.38) MAPTUSP2ALDH1A1NSD2
SCHEMBL14830332 0.71 USP2 (0.35) MAPTUSP2KMT2ALMNAALDH1A1
SCHEMBL14830272 0.70 MTNR1A (0.52) MAPTALDH1A1
SCHEMBL14830271 0.70 MTNR1A (0.52) MAPTALDH1A1
SCHEMBL14838802 0.70 MTNR1A (0.38) MAPTKMT2ALMNAALDH1A1RAB9A
SCHEMBL29051390 0.66 USP2 (0.35) MAPTUSP2ALDH1A1NSD2
SCHEMBL14720810 0.66 USP2 (0.35) MAPTUSP2ALDH1A1NSD2
SCHEMBL27917658 0.66 PPARG (0.42) MAPTLMNAALDH1A1POLBSMN1; SMN2
SCHEMBL14830782 0.66 ALOX15 (0.40) MAPTUSP2ALDH1A1NSD2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013046211-A1 PROCESSES FOR THE PREPARATION OF 5-CHLORO-N-({(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL) PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)-2-THIOPHENE-CARBOXAMIDE AND INTERMEDIATES THEREOF SYMED LABS LIMITED (IN) 2013-04-04 WO disclosed