Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14830784 | 0.78 | AR (0.40) | USP2MAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14830333 | 0.77 | ALDH1A1 (0.43) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14830582 | 0.77 | ALOX15 (0.38) | USP2MAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL14830271 | 0.75 | MTNR1A (0.52) | MAPTL3MBTL1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL14830272 | 0.75 | MTNR1A (0.52) | MAPTL3MBTL1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL14838802 | 0.74 | MTNR1A (0.38) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL29051390 | 0.73 | USP2 (0.35) | USP2MAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL14720810 | 0.73 | USP2 (0.35) | USP2MAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL14830331 | 0.71 | MAPT (0.33) | USP2MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL27917658 | 0.70 | PPARG (0.42) | MAPTL3MBTL1ALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013046211-A1 | PROCESSES FOR THE PREPARATION OF 5-CHLORO-N-({(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL) PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)-2-THIOPHENE-CARBOXAMIDE AND INTERMEDIATES THEREOF | SYMED LABS LIMITED (IN) | 2013-04-04 | — | — | WO | disclosed |