Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | RNF4 | P78317 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14830582 | 0.77 | ALOX15 (0.38) | ALOX15ATML3MBTL1TDP1HPGD | |
| SCHEMBL4740194 | 0.77 | ALDH1A1 (0.42) | ALOX15ATML3MBTL1TDP1HPGD | |
| SCHEMBL8995660 | 0.75 | ATM (0.45) | ALOX15ATML3MBTL1TDP1HPGD | |
| SCHEMBL14838802 | 0.74 | MTNR1A (0.38) | ALOX15ATML3MBTL1TDP1MAPT | |
| SCHEMBL29001732 | 0.73 | ATM (0.40) | ALOX15ATML3MBTL1TDP1HPGD | |
| SCHEMBL4492405 | 0.73 | ALOX15 (0.43) | ALOX15ATML3MBTL1TDP1HPGD | |
| Ethylene SCHEMBL2021059 | 0.72 | TDP1 (0.50) | ALOX15ATML3MBTL1TDP1HPGD | |
| SCHEMBL14830271 | 0.72 | MTNR1A (0.52) | L3MBTL1MAPTALDH1A1MTNR1AMTNR1B | |
| SCHEMBL9241160 | 0.72 | TDP1 (0.54) | ALOX15ATML3MBTL1TDP1HPGD | |
| SCHEMBL18073 | 0.72 | TDP1 (0.54) | ALOX15ATML3MBTL1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013046211-A1 | PROCESSES FOR THE PREPARATION OF 5-CHLORO-N-({(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL) PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)-2-THIOPHENE-CARBOXAMIDE AND INTERMEDIATES THEREOF | SYMED LABS LIMITED (IN) | 2013-04-04 | — | — | WO | disclosed |