Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18522592 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTNPC1RAB9AF2RL1 | |
| SCHEMBL13840019 | 0.92 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTNPC1RAB9AF2RL1 | |
| SCHEMBL28028229 | 0.91 | POLB (0.52) | SMN1; SMN2MAPTNPC1RAB9AF2RL1 | |
| SCHEMBL11921516 | 0.90 | THRB (0.55) | SMN1; SMN2MAPTNPC1RAB9APOLB | |
| SCHEMBL22566492 | 0.88 | THRB (0.53) | SMN1; SMN2MAPTNPC1RAB9APOLB | |
| SCHEMBL16661789 | 0.88 | MAPT (0.53) | SMN1; SMN2MAPTNPC1RAB9AF2RL1 | |
| SCHEMBL8640696 | 0.88 | ALDH1A1 (0.48) | SMN1; SMN2MAPTNPC1RAB9AF2RL1 | |
| SCHEMBL17036777 | 0.87 | POLB (0.58) | SMN1; SMN2MAPTNPC1RAB9APOLB | |
| SCHEMBL18869110 | 0.87 | POLB (0.49) | SMN1; SMN2MAPTNPC1RAB9AF2RL1 | |
| SCHEMBL19499848 | 0.87 | POLB (0.49) | SMN1; SMN2MAPTNPC1RAB9AF2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 480 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC (CH) | 2026-01-01 | — | — | US | claimed |
| US-12492275-B2 | Photo-curable compositions containing high refractive index monomers for use in 3D printing applications | ARKEMA FRANCE (FR) | 2025-12-09 | — | — | US | claimed |
| US-12379611-B2 | Diffractive contact lenses | ALCON INC. (CH) | 2025-08-05 | — | — | US | claimed |
| EP-4522665-A1 | RADIATION INDUCED RADICAL CURING BY SEMICONDUCTING NANOPARTICLES | Yeda Research and Development Co. Ltd (IL) | 2025-03-19 | — | — | EP | claimed |
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| US-20240142665-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2024-05-02 | — | — | US | claimed |
| EP-4356169-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-04-24 | — | — | EP | claimed |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2024-04-11 | — | — | US | claimed |
| US-20240052081-A1 | PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS | ARKEMA FRANCE (FR) | 2024-02-15 | — | — | US | claimed |
| EP-4284787-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-12-06 | — | — | EP | claimed |
| US-20050055090-A1 | Process for manufacturing intraocular lenses with blue light absorption characteristics | BAUSCH HEALTH US, LLC | 2005-03-10 | — | — | US | claimed |
| EP-0914169-B1 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LAB INC (US) | 2003-07-30 | — | — | EP | claimed |
| EP-0914169-A3 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LABORATORIES, INC. (US) | 2002-08-28 | — | — | EP | claimed |
| US-6353069-B1 | INTRAOCULAR LENSES THAT HAVE HIGH REFRACTIVE INDEXES, ARE FLEXIBLE AND TRANSPARENT, CAN BE INSERTED INTO EYE THROUGH RELATIVELY SMALL INCISION, RECOVER ORIGINAL SHAPE AFTER HAVING BEEN INSERTED, AND ARE FREE OF GLISTENINGS | ALCON MANUFACTURING, LTD. | 2002-03-05 | — | — | US | claimed |
| CN-1290352-A | High refractive index ophthalmic device mafterials | ALCON LAB INC (US) | 2001-04-04 | — | — | CN | claimed |
| EP-1080382-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | Alcon Laboratories, Inc. (US) | 2001-03-07 | — | — | EP | claimed |
| US-6001128-A | CROSSLINKED ACRYLATED ESTER | ALCON LABORATORIES, INC. (US) | 1999-12-14 | — | — | US | claimed |
| WO-1999053347-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
| EP-0914169-A2 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LABORATORIES, INC. (US) | 1999-05-12 | — | — | EP | claimed |
| WO-1998053862-A2 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LABORATORIES, INC. (US) | 1998-12-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | LBR, CRYZ, CRYAA | SMN1; SMN2 4324/4885MAPT 2700/4885NPC1 4517/4885 |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, UACA, PDE6A | SMN1; SMN2 4546/4885MAPT 536/4885NPC1 4720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.