Potassium Ion

SCHEMBL14844933

CC(NC(=S)[S-])N(C(C)NC(=S)[S-])C(C)NC(=S)[S-].[K+].[K+].[K+]

nearest known ligand 0.50

Known targets — ChEMBL curated mechanism

AGTR1 DHFR GABBR1 GABBR2 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ GART NR3C2 PBP2X PTGS1 PTGS2 VKORC1 bla blaT-3 blaT-4 blaT-5 blaT-6 dacA dacB dacC folA ftsI mrcA mrcB mrdA pbp1a pbp1b pbp2a pbp2b pbp3 pol thyA

The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	CA12	O43570	9/20	0.50

▸	CA1	P00915	9/20	0.50

▸	CA2	P00918	9/20	0.50

▸	CA9	Q16790	9/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Zinc Ion SCHEMBL10542658	0.69	CA12 (0.36)	CA12CA1CA2CA9
Potassium Ion SCHEMBL14844197	0.67	—	—
Potassium Ion SCHEMBL23014513	0.66	—	—
Potassium Ion SCHEMBL10936805	0.65	CA2 (0.46)	CA12CA1CA2CA9
SCHEMBL8085242	0.65	CA12 (0.46)	CA12CA1CA2CA9
SCHEMBL8085245	0.65	CA12 (0.46)	CA12CA1CA2CA9
SCHEMBL9124199	0.62	CA12 (0.91)	CA12CA1CA2CA9
SCHEMBL11236948	0.62	—	—
SCHEMBL5157751	0.61	ALDH1A1 (0.39)	CA2
Metam SCHEMBL202666	0.60	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013050426-A1	CARBONIC ANHYDRASE INHIBITOR COMPRISING A DITHIOCARBAMATE	UNIVERSITETET I OSLO (NO)	2013-04-11	—	—	WO	disclosed