Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848484 | 0.88 | KDM4E (0.44) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL14848497 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL14848452 | 0.80 | NOTUM (0.44) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL14848457 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10PKMMEN1 | |
| SCHEMBL9550442 | 0.77 | MAOA (0.51) | ALDH1A1HPGDKDM4EPKMMEN1 | |
| SCHEMBL7103671 | 0.71 | ACLY (0.56) | ALDH1A1HPGDKDM4EPKMMEN1 | |
| SCHEMBL14848593 | 0.71 | HPGD (0.47) | ALDH1A1HPGDKDM4EPKMMEN1 | |
| SCHEMBL14097520 | 0.70 | KDM4E (0.52) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL7353766 | 0.70 | KMT2A (0.51) | KDM4EHTTKMT2ARAB9ACYP2D6 | |
| SCHEMBL1554320 | 0.70 | KDM4E (0.53) | ALDH1A1HPGDKDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933075-B2 | Compounds useful as antiviral agents, compositions, and methods of use | FUZIANS BIOMEDICALS, INC. (KY) | 2015-01-13 | — | — | US | disclosed |
| US-20130090339-A1 | COMPOUNDS USEFUL AS ANTIVIRAL AGENTS, COMPOSITIONS, AND METHODS OF USE | THE UAB RESEARCH FOUNDATION (US) | 2013-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090339-A1 | COMPOUNDS USEFUL AS ANTIVIRAL AGENTS, COMPOSITIONS, AND METHODS OF USE | SAMHD1, ZC3HAV1, DDX5 | ALDH1A1 3597/4885HPGD 3316/4885KDM4E 3711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.