SCHEMBL1484965

SCHEMBL1484965

c1ccc(N2CCCNCC2)nc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLD1 Q13393 1/20 0.86
ALDH1A1 P00352 6/20 0.62
HSD17B10 Q99714 4/20 0.62
CYP3A4 P08684 3/20 0.62
HPGD P15428 3/20 0.62
USP2 O75604 2/20 0.62
CYP2D6 P10635 2/20 0.62
CYP2C9 P11712 2/20 0.62
TSHR P16473 2/20 0.62
CYP2C19 P33261 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
MEN1 O00255 1/20 0.62
MAPK1 P28482 1/20 0.62
KMT2A Q03164 1/20 0.62
CYP1A2 P05177 2/20 0.60
KDM4E B2RXH2 2/20 0.53
CHRNB2 P17787 2/20 0.51
CHRNA4 P43681 2/20 0.51
BPTF Q12830 1/20 0.51
PRKCA P17252 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29844434 1.00 PLD1 (0.86) PLD1ALDH1A1HSD17B10CYP3A4HPGD
SCHEMBL7900 0.93 PLD1 (1.00) PLD1ALDH1A1HSD17B10CYP3A4HPGD
SCHEMBL893565 0.93 PLD1 (1.00) PLD1ALDH1A1HSD17B10CYP3A4HPGD
SCHEMBL29400889 0.93 PLD1 (1.00) PLD1ALDH1A1HSD17B10CYP3A4HPGD
Hydrochloric Acid SCHEMBL27481639 0.91 PLD1 (0.96) PLD1ALDH1A1HSD17B10CYP3A4HPGD
Piperazine SCHEMBL27920772 0.91 PLD1 (0.96) PLD1ALDH1A1HSD17B10CYP3A4HPGD
Hydrochloric Acid SCHEMBL6349557 0.91 PLD1 (0.96) PLD1ALDH1A1HSD17B10CYP3A4HPGD
Ammonia Solution, Strong SCHEMBL17926100 0.91 PLD1 (0.96) PLD1ALDH1A1HSD17B10CYP3A4HPGD
Hydrochloric Acid SCHEMBL4165242 0.91 PLD1 (0.96) PLD1ALDH1A1HSD17B10CYP3A4HPGD
Bromide SCHEMBL11807389 0.91 PLD1 (0.96) PLD1ALDH1A1HSD17B10CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115093794-B Polysilicon polishing composition and application thereof 万华化学集团电子材料有限公司 2023-10-13 CN claimed
CN-115093794-A Polysilicon polishing composition and application thereof 万华化学集团电子材料有限公司 2022-09-23 CN claimed
EP-4321504-B1 PEGYLATED LIPID AND LIPOSOME MODIFIED THEREBY, AND PHARMACEUTICAL COMPOSITION COMPRISING LIPOSOME AND PREPARATION AND USE THEREOF XIAMEN SINOPEG BIOTECH CO LTD (CN) 2026-02-18 EP disclosed
US-20250288531-A1 AMINO ACID-BASED CATIONIC LIPID CONTAINING UNSATURATED BONDS XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2025-09-18 US disclosed
EP-4534525-A1 AMINO ACID-BASED CATIONIC LIPID CONTAINING UNSATURATED BONDS Xiamen Sinopeg Biotech Co., Ltd. (CN) 2025-04-09 EP disclosed
US-20240197633-A1 PEGYLATED LIPID, LIPOSOME MODIFIED BY THE LIPID, PHARMACEUTICAL COMPOSITION CONTAINING THE LIPOSOME, FORMULATION AND APPLICATION THEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2024-06-20 US disclosed
US-20240199555-A1 APPLICATIONS OF BIASED LIGANDS OF THE SEROTONIN 5-HT7 RECEPTOR FOR THE TREATMENT OF PAIN, MULTIPLE SCLEROSIS AND THE CONTROL OF THERMOREGULATION Université d'Orléans (FR) 2024-06-20 US disclosed
US-12006301-B1 And synthesis of dual 5-HT1A and 5-HT7 receptor ligands FLORIDA A&M UNIVERSITY (US) 2024-06-11 US disclosed
US-20240180951-A1 PEGYLATED LIPID, LIPOSOME MODIFIED BY THE LIPID, PHARMACEUTICAL COMPOSITION CONTAINING THE LIPOSOME, FORMULATION AND APPLICATION THEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2024-06-06 US disclosed
EP-4321504-A1 PEGYLATED LIPID AND LIPOSOME MODIFIED THEREBY, AND PHARMACEUTICAL COMPOSITION COMPRISING LIPOSOME AND PREPARATION AND USE THEREOF Xiamen Sinopeg Biotech Co., Ltd. (CN) 2024-02-14 EP disclosed
EP-4321503-A1 PEGYLATED LIPID, LIPOSOME MODIFIED THEREBY, PHARMACEUTICAL COMPOSITION CONTAINING LIPOSOME, PREPARATION THEREOF, AND USE THEREOF Xiamen Sinopeg Biotech Co., Ltd. (CN) 2024-02-14 EP disclosed
EP-1419150-A2 PHENYLSULFONYL-1,3-DIHYDRO-2H-INDOLE-2-ONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE Sanofi-Aventis (FR) 2004-05-19 EP disclosed
US-20040063713-A1 Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction ABBVIE INC. 2004-04-01 US disclosed
US-20040002488-A1 Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction WEINSTOCK, STEVEN F. 2004-01-01 US disclosed
WO-2003008407-A2 PHENYLSULFONYL-1,3-DIHYDRO-2H-INDOLE-2-ONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE SANOFI-SYNTHELABO (FR) 2003-01-30 WO disclosed
EP-1243268-A1 MEDICINAL COMPOSITION Nippon Shinyaku Co., Ltd. (JP) 2002-09-25 EP disclosed
US-20020045618-A1 Heteroaryl diazacycloalkanes, their preparation and use NEUROSEARCH A/S (DK) 2002-04-18 US disclosed
EP-1175416-A1 HETEROARYL DIAZACYCLOALKANES, THEIR PREPARATION AND USE NEUROSEARCH A/S (DK) 2002-01-30 EP disclosed
EP-1156045-A1 AMIDE DERIVATIVES AND DRUG COMPOSITIONS Nippon Shinyaku Co., Ltd. (JP) 2001-11-21 EP disclosed
WO-2000064885-A1 HETEROARYL DIAZACYCLOALKANES, THEIR PREPARATION AND USE NEUROSEARCH A/S (DK) 2000-11-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240180951-A1 PEGYLATED LIPID, LIPOSOME MODIFIED BY THE LIPID, PHARMACEUTICAL COMPOSITION CONTAINING THE LIPOSOME, FORMULATION AND APPLICATION THEREOF LIPG, PHOSPHO1, LDLR PLD1 538/4885ALDH1A1 4614/4885HSD17B10 3074/4885
US-20020045618-A1 Heteroaryl diazacycloalkanes, their preparation and use CHRNA5, CHRNA7, CHRNA3 PLD1 1690/4885ALDH1A1 1310/4885HSD17B10 600/4885
US-20040063713-A1 Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction CYP19A1, CYP17A1, HSD17B11 PLD1 3391/4885ALDH1A1 246/4885HSD17B10 141/4885
US-12006301-B1 And synthesis of dual 5-HT1A and 5-HT7 receptor ligands HTR7, HTR1A, HTR5A PLD1 1228/4885ALDH1A1 1779/4885HSD17B10 2315/4885
US-20240197633-A1 PEGYLATED LIPID, LIPOSOME MODIFIED BY THE LIPID, PHARMACEUTICAL COMPOSITION CONTAINING THE LIPOSOME, FORMULATION AND APPLICATION THEREOF LIPG, LDLR, LIPA PLD1 565/4885ALDH1A1 4449/4885HSD17B10 3334/4885
US-20040002488-A1 Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction CYP19A1, CYP17A1, HSD17B11 PLD1 3391/4885ALDH1A1 246/4885HSD17B10 141/4885
US-20250288531-A1 AMINO ACID-BASED CATIONIC LIPID CONTAINING UNSATURATED BONDS SLC7A1, LNPEP, SLC1A5 PLD1 380/4885ALDH1A1 2947/4885HSD17B10 2045/4885
US-20240199555-A1 APPLICATIONS OF BIASED LIGANDS OF THE SEROTONIN 5-HT7 RECEPTOR FOR THE TREATMENT OF PAIN, MULTIPLE SCLEROSIS AND THE CONTROL OF THERMOREGULATION HTR7, HTR1A, CNR1 PLD1 2174/4885ALDH1A1 1323/4885HSD17B10 1393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.