Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14850070 | 0.85 | LMNA (0.49) | LMNAMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL18748269 | 0.84 | TSHR (0.45) | LMNAMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL14850363 | 0.81 | L3MBTL1 (0.61) | MAPK1HTTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3794601 | 0.80 | L3MBTL1 (0.53) | MAPK1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4640550 | 0.80 | LTA4H (0.46) | LMNAMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL19404700 | 0.80 | KDM4E (0.47) | LMNAHTTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14850360 | 0.80 | AHR (0.43) | LMNAHTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL14850369 | 0.80 | L3MBTL1 (0.43) | LMNAHTTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6232233 | 0.80 | THRA (0.43) | LMNAMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL3785269 | 0.79 | CYP1A2 (0.58) | MAPK1HTTALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216979-B2 | Antimicrobial compounds and methods of making and using the same | MELINTA THERAPEUTICS, INC. (US) | 2015-12-22 | — | — | US | disclosed |
| US-20130090326-A1 | Antimicrobial Compounds and Methods of Making and Using the Same | RIB-X PHARMACEUTICALS, INC. (US) | 2013-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090326-A1 | Antimicrobial Compounds and Methods of Making and Using the Same | MPO, LPO, CAT | LMNA 2222/4885MAPK1 3970/4885HTT 1768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.