Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14865362 | 0.88 | P2RX7 (0.37) | P2RX7CNR2MAPK9MAPK10PTGES | |
| SCHEMBL2805291 | 0.84 | P2RX7 (0.39) | P2RX7KMT2ACNR2MEN1 | |
| SCHEMBL14865374 | 0.83 | CNR2 (0.39) | P2RX7HTTCNR2 | |
| SCHEMBL2805217 | 0.83 | P2RX7 (0.36) | P2RX7HTTCNR2 | |
| SCHEMBL13159664 | 0.81 | ALDH1A1 (0.39) | P2RX7HTTKMT2AMEN1 | |
| SCHEMBL186187 | 0.81 | TRPV1 (0.36) | P2RX7HTTKMT2AMEN1 | |
| SCHEMBL14865331 | 0.81 | ROCK2 (0.34) | P2RX7HTTCNR2MAPK9MAPK10 | |
| SCHEMBL2808176 | 0.80 | BDKRB1 (0.36) | P2RX7HTTCNR2 | |
| SCHEMBL197308 | 0.80 | BDKRB1 (0.36) | P2RX7HTTCNR2 | |
| SCHEMBL13128961 | 0.79 | CNR2 (0.40) | P2RX7CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |