SCHEMBL14865384

SCHEMBL14865384

CC1=Nc2ccccc2NC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.38
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MAPT P10636 7/20 0.35
GAA P10253 5/20 0.35
MCL1 Q07820 1/20 0.35
BRPF1 P55201 1/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 5/20 0.35
DRD2 P14416 3/20 0.35
DRD4 P21917 2/20 0.35
MAPK1 P28482 2/20 0.34
NPC1 O15118 1/20 0.34
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
LMNA P02545 3/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HTT P42858 1/20 0.33
JAK2 O60674 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionaldehyde SCHEMBL28298809 0.87 LMNA (0.35) RAB9AMAPTGAABRPF1ALDH1A1
SCHEMBL28298808 0.85 LMNA (0.39) MAPTGAABRPF1ALDH1A1KDM4E
SCHEMBL8805818 0.80 BRD4 (0.41) RAB9AMAPTGAAMCL1ALDH1A1
SCHEMBL13211831 0.76 DRD2 (0.37) RAB9AHSD17B10MAPTGAAALDH1A1
SCHEMBL24289878 0.75 ALOX15 (0.36) RAB9AALOX15HSD17B10MAPTGAA
SCHEMBL4111485 0.75 NOS2 (0.44) RAB9AALOX15HSD17B10MAPTGAA
SCHEMBL8317265 0.75 ALOX15 (0.36) RAB9AALOX15HSD17B10MAPTGAA
SCHEMBL13474009 0.75 MAPT (0.38) RAB9AALOX15HSD17B10MAPTGAA
SCHEMBL30164443 0.75 RAB9A (0.35) RAB9AALOX15HSD17B10MAPTGAA
SCHEMBL15223291 0.75 MAPT (0.35) RAB9AALOX15HSD17B10MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2793311-B1 METAL COMPLEX DYE, PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, DYE SOLUTION, AND COMPOUND FUJIFILM CORP (JP) 2019-06-19 EP disclosed
CN-106029076-B Benzo piperazine composition as BET bromine domain inhibitor 福马疗法公司 2019-06-07 CN disclosed
EP-1651012-B1 WHITE ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO (JP) 2013-04-17 EP disclosed