Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24289878 | 0.75 | ALOX15 (0.36) | ALOX15HSD17B10ALDH1A1RAB9AMAPT | |
| SCHEMBL4111485 | 0.75 | NOS2 (0.44) | ALOX15HSD17B10ALDH1A1RAB9AMAPT | |
| SCHEMBL28284830 | 0.75 | ALOX15 (0.36) | ALOX15HSD17B10ALDH1A1RAB9AMAPT | |
| SCHEMBL14865384 | 0.75 | RAB9A (0.38) | ALOX15HSD17B10ALDH1A1RAB9AMAPT | |
| SCHEMBL28191426 | 0.75 | ALOX15 (0.36) | ALOX15HSD17B10ALDH1A1RAB9AMAPT | |
| SCHEMBL3952885 | 0.73 | ALDH1A1 (0.38) | ALOX15HSD17B10ALDH1A1RAB9AMAPT | |
| SCHEMBL17533329 | 0.72 | ALDH1A1 (0.56) | ALDH1A1RAB9AMAPTKDM4EGAA | |
| SCHEMBL5727673 | 0.72 | NOS3 (0.34) | ALOX15HSD17B10ALDH1A1RAB9AMAPT | |
| SCHEMBL31319868 | 0.72 | NOS3 (0.34) | ALOX15HSD17B10ALDH1A1RAB9AMAPT | |
| SCHEMBL13474009 | 0.71 | MAPT (0.38) | ALOX15HSD17B10ALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556749-A1 | N-2-(hetero)arylethylcarboxamide derivative, and pest-controlling agent comprising the same | Nihon Nohyaku Co., Ltd. (JP) | 2013-02-13 | — | — | EP | disclosed |
| CN-1068201-C | Inhibitor of intiltration of acidophilic leukocyte | TORAY INDUSTRIES (JP) | 2001-07-11 | — | — | CN | disclosed |
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0295797-B1 | Process for the selective reduction of 2-quinoxalinol-4-oxides to 2-quinoxalinols | UNIROYAL CHEM CO INC (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| CN-1033327-C | Process for preparing tricyclotriazolo derivatives and their use | TORAY INDUSTRIES (JP) | 1996-11-20 | — | — | CN | disclosed |
| US-5478823-A | Antiinflammatory agents, antiallergens; tricyclic triazolo derivative | TORAY INDUSTRIES, INC. (JP) | 1995-12-26 | — | — | US | disclosed |
| CN-1095594-A | Inhibitor of intiltration of acidophilic leukocyte | TORAY INDUSTRIES (JP) | 1994-11-30 | — | — | CN | disclosed |
| EP-0617961-A1 | EOSINOPHIL INFILTRATION INHIBITOR | TORAY INDUSTRIES, INC. (JP) | 1994-10-05 | — | — | EP | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |
| EP-0266102-B1 | QUINOXALINONE DERIVATIVES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| CN-1066849-A | Three ring triazolo derivatives, its Manufacturing approach and use | TORAY INDUSTRIES (JP) | 1992-12-09 | — | — | CN | disclosed |
| WO-1992005160-A1 | 4-ARYLSULFONYL-3,4-DIHYDRO-2(1H)-QUINOXALINONE-1-ALKANOIC ACIDS, ESTERS, AND SALTS | SARGES REINHARD (US) | 1992-04-02 | — | — | WO | disclosed |
| US-4940708-A | 4-arylsulfonyl-3,4-dihydro-2(1H)-quinoxalinone-1-alkanoic acids, esters, and salts | PFIZER INC. (US) | 1990-07-10 | — | — | US | disclosed |
| US-4814444-A | SULFIDED PLATINUM, SULFIDED PALLADIUM, OR SULFIDED RHODIUM REDUCING CATALYSTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0295815-A2 | Process for production of 2-quinoxalines | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1988-12-21 | — | — | EP | disclosed |
| EP-0295797-A2 | Process for the selective reduction of 2-quinoxaline-4-oxides | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1988-12-21 | — | — | EP | disclosed |
| EP-0266102-A2 | Quinoxalinone derivatives | PFIZER INC. (US) | 1988-05-04 | — | — | EP | disclosed |