SCHEMBL14868664

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14868584	0.85	RIPK1 (0.48)	ALOX5RIPK1ADRA2AADRA2BADRA2C
	SCHEMBL14868723	0.78	ALOX5 (0.38)	ALOX5RIPK1ADRA2AADRA2BADRA2C
	SCHEMBL14868666	0.78	ADRA2A (0.38)	ALOX5RIPK1ADRA2AADRA2BADRA2C
	SCHEMBL14868751	0.77	ALOX5 (0.41)	ALOX5ALDH1A1KMT2AKDM4EHPGD
	SCHEMBL14868665	0.75	RAB9A (0.46)	ALOX5ADRA2AADRA2BADRA2CRAB9A
	SCHEMBL14868825	0.73	ALOX5 (0.39)	ALOX5
	SCHEMBL14868678	0.73	HSD11B1 (0.46)	RIPK1ADRA2AADRA2BADRA2CHSD11B1
	SCHEMBL20799765	0.72	RAB9A (0.38)	RIPK1RAB9AALDH1A1KMT2ANPC1
	SCHEMBL14868609	0.72	KMT2A (0.49)	ALDH1A1KMT2AL3MBTL1KDM4EHSD17B10
	SCHEMBL6659364	0.71	TAAR1 (0.45)	ALOX5RIPK1RAB9AALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.