Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | AHCY | P23526 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14878440 | 0.93 | ALDH1A1 (0.37) | ALDH1A1GAASMN1; SMN2KMT2AMMP8 | |
| SCHEMBL12905475 | 0.92 | KMT2A (0.35) | ALDH1A1HTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL14959560 | 0.92 | ALDH1A1 (0.36) | ALDH1A1GAAKMT2AMAPTMMP8 | |
| SCHEMBL14878421 | 0.92 | GAA (0.36) | ALDH1A1GAASMN1; SMN2KMT2AMAPT | |
| SCHEMBL779081 | 0.90 | MMP1 (0.46) | MMP8MMP3MMP2MMP9 | |
| SCHEMBL14878422 | 0.89 | POLB (0.44) | ALDH1A1GAAHTTSMN1; SMN2KMT2A | |
| SCHEMBL14878434 | 0.86 | MMP1 (0.36) | ALDH1A1KMT2AMMP8MMP3MEN1 | |
| SCHEMBL14878475 | 0.85 | MMP1 (0.37) | KMT2AMMP3MEN1MMP9HRH3 | |
| SCHEMBL14878474 | 0.85 | L3MBTL1 (0.38) | ALDH1A1HTTSMN1; SMN2KMT2AMMP3 | |
| SCHEMBL14878402 | 0.85 | ITGA4 (0.37) | ALDH1A1KMT2AMAPTMMP8MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426415-B2 | Human ADAM-10 inhibitors | SYMPHONY EVOLUTION, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| EP-2436676-A1 | Human adam-10 inhibitors | Symphony Evolution, Inc. (US) | 2012-04-04 | — | — | EP | disclosed |