Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.36 |
| ▸ | MMP13 | P45452 | 4/20 | 0.36 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | MMP7 | P09237 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12905479 | 0.92 | ALDH1A1 (0.38) | MMP1MMP13MMP3MMP9MMP7 | |
| SCHEMBL16507896 | 0.90 | MMP1 (0.41) | MMP1MMP13MMP3MMP9MMP7 | |
| SCHEMBL778885 | 0.90 | MMP1 (0.49) | MMP1MMP13MMP3MMP9MMP7 | |
| SCHEMBL14878436 | 0.89 | KMT2A (0.39) | MMP1MMP13MMP3MMP9MMP7 | |
| SCHEMBL14878440 | 0.87 | ALDH1A1 (0.37) | MMP1MMP13MMP3MMP9MMP7 | |
| SCHEMBL14878480 | 0.87 | MMP9 (0.47) | MMP1MMP13MMP3MMP9MMP7 | |
| SCHEMBL14878481 | 0.86 | MMP3 (0.41) | MMP1MMP13MMP3MMP9MMP7 | |
| SCHEMBL14878433 | 0.86 | ALDH1A1 (0.38) | MMP3MMP9MMP8ALDH1A1KMT2A | |
| SCHEMBL14878402 | 0.86 | ITGA4 (0.37) | MMP1MMP13MMP3MMP9MMP7 | |
| SCHEMBL14878421 | 0.85 | GAA (0.36) | MMP13MMP3MMP9MMP8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426415-B2 | Human ADAM-10 inhibitors | SYMPHONY EVOLUTION, INC. (US) | 2013-04-23 | — | — | US | disclosed |