Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 5/20 | 0.40 |
| ▸ | MMP9 | P14780 | 5/20 | 0.40 |
| ▸ | MMP13 | P45452 | 5/20 | 0.40 |
| ▸ | MMP3 | P08254 | 5/20 | 0.40 |
| ▸ | MMP7 | P09237 | 4/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12905415 | 0.92 | SOS1 (0.41) | SOS1FPR1MMP1MMP9MMP13 | |
| SCHEMBL779126 | 0.90 | MMP1 (0.52) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14878404 | 0.87 | ITGB1 (0.39) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14878435 | 0.86 | MMP9 (0.42) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14878453 | 0.86 | MMP1 (0.37) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14878457 | 0.85 | MDM2 (0.41) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14878403 | 0.85 | MMP3 (0.35) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14878472 | 0.84 | FPR2 (0.39) | SOS1MMP1MMP9MMP13MMP3 | |
| SCHEMBL14878476 | 0.84 | L3MBTL1 (0.39) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14878449 | 0.83 | MMP1 (0.38) | MMP1MMP9MMP13MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426415-B2 | Human ADAM-10 inhibitors | SYMPHONY EVOLUTION, INC. (US) | 2013-04-23 | — | — | US | disclosed |