Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.46 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.46 |
| ▸ | RPS17 | P08708 | 1/20 | 0.46 |
| ▸ | RPSA | P08865 | 1/20 | 0.46 |
| ▸ | RPS2 | P15880 | 1/20 | 0.46 |
| ▸ | RPL35A | P18077 | 1/20 | 0.46 |
| ▸ | RPL7 | P18124 | 1/20 | 0.46 |
| ▸ | RPL17 | P18621 | 1/20 | 0.46 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.46 |
| ▸ | RPS3 | P23396 | 1/20 | 0.46 |
| ▸ | RPS12 | P25398 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12683627 | 1.00 | LMNA (0.67) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL12494026 | 1.00 | LMNA (0.67) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL15240172 | 0.88 | LMNA (0.52) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL15240173 | 0.88 | LMNA (0.52) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL12413849 | 0.85 | LMNA (0.71) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL14568970 | 0.84 | LMNA (0.66) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL7091990 | 0.84 | LMNA (0.66) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL15241055 | 0.84 | LMNA (0.48) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL15241053 | 0.84 | LMNA (0.48) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL12683703 | 0.84 | LMNA (0.65) | LMNACYP3A4MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9428528-B2 | Phenicol antibacterials | ZOETIS SERVICES LLC (US) | 2016-08-30 | — | — | US | disclosed |
| US-20160194342-A1 | PHENICOL ANTIBACTERIALS | ZOETIS SERVICES LLC (US) | 2016-07-07 | — | — | US | disclosed |
| US-9340564-B2 | Phenicol antibacterials | ZOETIS SERVICES LLC (US) | 2016-05-17 | — | — | US | disclosed |
| US-9206126-B2 | Phenicol antibacterial agents | ZOETIS SERVICES LLC (US) | 2015-12-08 | — | — | US | disclosed |
| US-20150344412-A1 | NOVEL PHENICOL ANTIBACTERIALS | ZOETIS SERVICES LLC (US) | 2015-12-03 | — | — | US | disclosed |
| US-9145355-B2 | Phenicol antibacterials | ZOETIS SERVICES LLC (US) | 2015-09-29 | — | — | US | disclosed |
| US-20150266910-A1 | PHENICOL ANTIBACTERIALS | ZOETIS SERVICES LLC (US) | 2015-09-24 | — | — | US | disclosed |
| EP-2900641-A1 | PHENICOL ANTIBACTERIAL AGENTS | Zoetis LLC (US) | 2015-08-05 | — | — | EP | disclosed |
| US-9073894-B2 | Phenicol antibacterials | ZOETIS SERVICES LLC (US) | 2015-07-07 | — | — | US | disclosed |
| EP-2822934-A1 | PHENICOL ANTIBACTERIALS | Zoetis LLC (US) | 2015-01-14 | — | — | EP | disclosed |
| US-20140303384-A1 | NOVEL PHENICOL ANTIBACTERIALS | ZOETIS SERVICES LLC | 2014-10-09 | — | — | US | disclosed |
| EP-2768798-A1 | NOVEL PHENICOL ANTIBACTERIALS | Zoetis LLC (US) | 2014-08-27 | — | — | EP | disclosed |
| US-20140088046-A1 | PHENICOL ANTIBACTERIAL AGENTS | ZOETIS LLC (US) | 2014-03-27 | — | — | US | disclosed |
| US-20130237502-A1 | PHENICOL ANTIBACTERIALS | ZOETIS SERVICES LLC | 2013-09-12 | — | — | US | disclosed |
| WO-2013134061-A1 | PHENICOL ANTIBACTERIALS | ZOETIS LLC (US) | 2013-09-12 | — | — | WO | disclosed |
| WO-2013057619-A1 | NOVEL PHENICOL ANTIBACTERIALS | AH USA 42 LLC (US) | 2013-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237502-A1 | PHENICOL ANTIBACTERIALS | MRPL21, TTL, CTSL | LMNA 2697/4885CYP3A4 17/4885MEN1 4010/4885 |
| US-20160194342-A1 | PHENICOL ANTIBACTERIALS | MRPL21, TTL, CTSL | LMNA 2697/4885CYP3A4 17/4885MEN1 4010/4885 |
| US-20140088046-A1 | PHENICOL ANTIBACTERIAL AGENTS | MRPL21, CLPP, CLPX | LMNA 2559/4885CYP3A4 41/4885MEN1 4152/4885 |
| US-20140303384-A1 | NOVEL PHENICOL ANTIBACTERIALS | MRPL21, CTSL, TTL | LMNA 2487/4885CYP3A4 83/4885MEN1 4261/4885 |
| US-20150344412-A1 | NOVEL PHENICOL ANTIBACTERIALS | MRPL21, CTSL, TTL | LMNA 2487/4885CYP3A4 83/4885MEN1 4261/4885 |
| US-20150266910-A1 | PHENICOL ANTIBACTERIALS | MRPL21, TTL, CTSL | LMNA 2697/4885CYP3A4 17/4885MEN1 4010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.