Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.46 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.46 |
| ▸ | RPS17 | P08708 | 1/20 | 0.46 |
| ▸ | RPSA | P08865 | 1/20 | 0.46 |
| ▸ | RPS2 | P15880 | 1/20 | 0.46 |
| ▸ | RPL35A | P18077 | 1/20 | 0.46 |
| ▸ | RPL7 | P18124 | 1/20 | 0.46 |
| ▸ | RPL17 | P18621 | 1/20 | 0.46 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.46 |
| ▸ | RPS3 | P23396 | 1/20 | 0.46 |
| ▸ | RPS12 | P25398 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19828494 | 0.88 | LMNA (0.56) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL1753533 | 0.86 | LMNA (0.70) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL9092856 | 0.85 | LMNA (0.67) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL14183019 | 0.85 | LMNA (0.67) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL14880947 | 0.85 | LMNA (0.67) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL12494026 | 0.85 | LMNA (0.67) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL12683627 | 0.85 | LMNA (0.67) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL14568970 | 0.84 | LMNA (0.66) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL7091990 | 0.84 | LMNA (0.66) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL14880788 | 0.84 | LMNA (0.70) | LMNACYP3A4MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130203857-A1 | Pharmaceutical Compositions for the Treatment of Bacterial Infections | NANOCORE BIOTECNOLOGIA S.A. (BR) | 2013-08-08 | — | — | US | disclosed |
| US-20130203858-A1 | Fast-Dissolving Solid Pharmaceutical Form for Treating Bacterial Infections | NANOCORE BIOTECNOLOGIA S.A. (BR) | 2013-08-08 | — | — | US | disclosed |
| US-8314252-B2 | Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol | INTERVET INC. (US) | 2012-11-20 | — | — | US | disclosed |
| WO-2012125832-A2 | ANTIMICROBIAL AGENTS | RIB-X PHARMACEUTICALS, INC. (US) | 2012-09-20 | — | — | WO | disclosed |
| US-20110166359-A1 | PROCESS FOR PREPARING OXAZOLINE-PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL | INTERVET INTERNATIONAL B.V. (NL) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203857-A1 | Pharmaceutical Compositions for the Treatment of Bacterial Infections | IL5, MYD88, TLR5 | LMNA 3468/4885CYP3A4 337/4885MEN1 2267/4885 |
| US-20110166359-A1 | PROCESS FOR PREPARING OXAZOLINE-PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL | PFAS, DHFR, OXA1L | LMNA 1876/4885CYP3A4 40/4885MEN1 1883/4885 |
| US-20130203858-A1 | Fast-Dissolving Solid Pharmaceutical Form for Treating Bacterial Infections | CFD, FASTKD5, SYK | LMNA 4079/4885CYP3A4 718/4885MEN1 3130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.