Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | RXRA | P19793 | 6/20 | 0.57 |
| ▸ | RXRB | P28702 | 5/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | BAD | Q92934 | 1/20 | 0.52 |
| ▸ | RXRG | P48443 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 3/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14961177 | 0.84 | ERN1 (0.47) | EGFRRXRARXRBPTPN1RXRG | |
| SCHEMBL14961176 | 0.84 | ERN1 (0.47) | EGFRRXRARXRBPTPN1RXRG | |
| SCHEMBL17208848 | 0.82 | BCL2L1 (0.60) | EGFRRXRARXRBBCL2L1BAD | |
| SCHEMBL22734016 | 0.82 | EGFR (0.72) | EGFRRXRARXRBBCL2L1BAD | |
| SCHEMBL21133280 | 0.82 | EGFR (0.72) | EGFRRXRARXRBBCL2L1BAD | |
| SCHEMBL23202431 | 0.82 | EGFR (0.72) | EGFRRXRARXRBBCL2L1BAD | |
| SCHEMBL864660 | 0.82 | EGFR (0.72) | EGFRRXRARXRBBCL2L1BAD | |
| SCHEMBL21133337 | 0.82 | EGFR (0.72) | EGFRRXRARXRBBCL2L1BAD | |
| SCHEMBL142861 | 0.82 | EGFR (0.72) | EGFRRXRARXRBBCL2L1BAD | |
| SCHEMBL30610361 | 0.82 | EGFR (0.72) | EGFRRXRARXRBBCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220023829-A1 | AMORPHOUS METAL ORGANIC FRAMEWORKS AND METHODS OF PREPARING THE SAME | ABSORPTION SOLUTIONS LLC | 2022-01-27 | — | — | US | disclosed |
| WO-2020117833-A2 | AMORPHOUS METAL ORGANIC FRAMEWORKS AND METHODS OF PREPARING THE SAME | FRAMERGY INC. (US) | 2020-06-11 | — | — | WO | disclosed |
| EP-3514159-A1 | ALUMINIUM METAL ORGANIC FRAMEWORK MATERIAL | The Texas A&M University System (US) | 2019-07-24 | — | — | EP | disclosed |
| EP-3143033-B1 | CHROMIUM METAL ORGANIC FRAMEWORKS AND SYNTHESIS OF METAL ORGANIC FRAMEWORKS | TEXAS A & M UNIV SYS (US) | 2019-04-10 | — | — | EP | disclosed |
| US-9951095-B2 | Chromium metal organic frameworks and synthesis of metal organic frameworks | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2018-04-24 | — | — | US | disclosed |
| US-9724668-B2 | Iron metal organic framework materials | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-08-08 | — | — | US | disclosed |
| US-20170050995-A1 | Chromium Metal Organic Frameworks and Synthesis of Metal Organic Frameworks | THE TEXAS A&M UNIVERSITY SYSTEM | 2017-02-23 | — | — | US | disclosed |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2016-12-01 | — | — | US | disclosed |
| EP-2876112-B1 | Monocrystalline iron metal organic frameworks | TEXAS A & M UNIV SYS (US) | 2016-07-13 | — | — | EP | disclosed |
| US-9102691-B2 | Aluminum metal organic framework materials | TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-08-11 | — | — | US | disclosed |
| WO-2015079229-A1 | PROCESS FOR PREPARING METAL ORGANIC FRAMEWORK MATERIALS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-06-04 | — | — | WO | disclosed |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2015-06-04 | — | — | US | disclosed |
| WO-2015079230-A1 | ALUMINIUM METAL ORGANIC FRAMEWORK MATERIALS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-06-04 | — | — | WO | disclosed |
| EP-2876112-A1 | Monocrystalline iron metal organic frameworks | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2015-05-27 | — | — | EP | disclosed |
| US-8915989-B2 | Porous coordination polymer, process for producing same, gas storage method, and gas separation method | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| US-8915989-B2 | Porous coordination polymer, process for producing same, gas storage method, and gas separation method | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| US-20130129608-A1 | POROUS COORDINATION POLYMER, PROCESS FOR PRODUCING SAME, GAS STORAGE METHOD, AND GAS SEPARATION METHOD | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130129608-A1 | POROUS COORDINATION POLYMER, PROCESS FOR PRODUCING SAME, GAS STORAGE METHOD, AND GAS SEPARATION METHOD | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2013-05-23 | — | — | US | disclosed |
| EP-2586766-A1 | POROUS METAL COMPLEX, PROCESS FOR PRODUCING SAME, GAS STORAGE METHOD, AND GAS SEPARATION METHOD | JX Nippon Oil & Energy Corporation (JP) | 2013-05-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050995-A1 | Chromium Metal Organic Frameworks and Synthesis of Metal Organic Frameworks | OXGR1, TFRC, PICALM | EGFR 313/4885RXRA 2502/4885RXRB 3146/4885 |
| US-20130129608-A1 | POROUS COORDINATION POLYMER, PROCESS FOR PRODUCING SAME, GAS STORAGE METHOD, AND GAS SEPARATION METHOD | SLC25A11, TMEM109, TCP1 | EGFR 1806/4885RXRA 4131/4885RXRB 4395/4885 |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | TFRC, FTH1, FECH | EGFR 1915/4885RXRA 4751/4885RXRB 4820/4885 |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | AS3MT, ORAI2, ORAI3 | EGFR 3558/4885RXRA 4007/4885RXRB 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.