SCHEMBL14890280

SCHEMBL14890280

CCC(c1cc(OC)ccc1C=CC(N)=O)[Si](OC)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.42
ALDH1A1 P00352 3/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
LY96 Q9Y6Y9 1/20 0.40
JUN P05412 1/20 0.39
NFKB1 P19838 1/20 0.39
KDM4E B2RXH2 2/20 0.39
TNFRSF1A P19438 1/20 0.39
TAS1R3 Q7RTX0 3/20 0.38
TAS1R1 Q7RTX1 3/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GLA P06280 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
RECQL P46063 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14890279 1.00 MAPT (0.42) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL14890417 0.89 ALDH1A1 (0.41) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL14890413 0.89 ALDH1A1 (0.41) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL2010382 0.83 NOS3 (0.40) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL8147548 0.72 MAPT (0.77) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL20227828 0.72 MAPT (0.54) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL7411020 0.72 MAPT (0.77) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL2010385 0.72 BCHE (0.43) ALDH1A1KDM4ETAS1R3TAS1R1NPC1
SCHEMBL5269733 0.71 KDM4E (0.46) MAPTALDH1A1MEN1KMT2ANFKB1
SCHEMBL11355877 0.71 MAPT (0.53) MAPTALDH1A1MEN1KMT2AJUN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921505-B2 Ultraviolet absorbing poly (organic oxidized silicon) particles having improved ultraviolet stability, and method for preparing same NANO AND MICRO TECHNOLOGIES CO., LTD. (KR) 2014-12-30 US disclosed
US-20130109824-A1 ULTRAVIOLET ABSORBING POLY (ORGANIC OXIDIZED SILICON) PARTICLES HAVING IMPROVED ULTRAVIOLET STABILITY, AND METHOD FOR PREPARING SAME NANO AND MICRO TECHNOLOGIES CO., LTD. (KR) 2013-05-02 US disclosed