Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL866268 | 1.00 | NPC1 (0.35) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL16114711 | 0.95 | EPHX1 (0.36) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Trimethylammonium SCHEMBL1707073 | 0.91 | ACHE (0.41) | EPHX1CA12CA14 | |
| Trimethylammonium SCHEMBL3681377 | 0.87 | TGFBR1 (0.36) | ALDH1A1TGFBR1 | |
| Trimethylammonium SCHEMBL5454852 | 0.87 | TGFBR1 (0.36) | ALDH1A1TGFBR1 | |
| Trimethylammonium SCHEMBL21743 | 0.86 | NPC1 (0.42) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL15846659 | 0.85 | ACHE (0.44) | EPHX1CA12CA14 | |
| Trimethylammonium SCHEMBL3277856 | 0.85 | NPC1 (0.37) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Sulfuric Acid SCHEMBL11210945 | 0.84 | EPHX1 (0.41) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Trimethylammonium SCHEMBL635942 | 0.84 | NPC1 (0.41) | NPC1GAAMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071462-A1 | ARTICLES COMPRISING AN OIL CAPTURE POLYMER | THE PROCTER & GAMBLE COMPANY (US) | 2018-04-19 | — | — | WO | claimed |
| US-20180100250-A1 | Articles Comprising an Oil Capture Polymer | THE PROCTER & GAMBLE COMPANY | 2018-04-12 | — | — | US | claimed |
| US-9895675-B2 | Soil adsorbing composites, compositions and methods for using same | THE PROCTER & GAMBLE COMPANY (US) | 2018-02-20 | — | — | US | claimed |
| EP-3274503-A1 | DURABLY ASSOCIATED SOIL ADSORBING COMPOSITES, COMPOSITIONS, AND METHODS FOR USING SAME | The Procter and Gamble Company (US) | 2018-01-31 | — | — | EP | claimed |
| EP-3274504-A1 | SOIL ADSORBING COMPOSITES, COMPOSITIONS, AND METHODS FOR USING SAME | The Procter and Gamble Company (US) | 2018-01-31 | — | — | EP | claimed |
| WO-2016160503-A1 | DURABLY ASSOCIATED SOIL ADSORBING COMPOSITES, COMPOSITIONS, AND METHODS FOR USING SAME | THE PROCTER & GAMBLE COMPANY (US) | 2016-10-06 | — | — | WO | claimed |
| US-20160279604-A1 | Soil Adsorbing Composites, Compositions and Methods for Using Same | THE PROCTER & GAMBLE COMPANY | 2016-09-29 | — | — | US | claimed |
| US-20160279603-A1 | Durably Associated Soil Adsorbing Composites, Compositions and Methods for Using Same | THE PROCTER & GAMBLE COMPANY | 2016-09-29 | — | — | US | claimed |
| EP-2219774-B1 | COLLOIDAL DISPERSION OF INORGANIC PARTICLES IN A LIQUID PHASE COMPRISING AN AMPHOLYTIC COPOLYMER | RHODIA OPERATIONS (FR) | 2016-07-13 | — | — | EP | claimed |
| EP-2340299-B1 | COPOLYMER FOR SURFACE PROCESSING OR MODIFICATION | RHODIA OPERATIONS (FR) | 2016-03-30 | — | — | EP | claimed |
| EP-1558658-B1 | CONTROLLED STRUCTURE COPOLYMER COMPRISING AN AMPHOTERIC OR ZWITTERIONIC PART | RHODIA CHIMIE SA (FR) | 2012-12-19 | — | — | EP | claimed |
| US-8163100-B2 | Synthetic microgel polymer compositions for treating and/or modifying hard surfaces | RHODIA OPERATIONS (FR) | 2012-04-24 | — | — | US | claimed |
| EP-1838762-B1 | COMPOSITION THAT CAN FORM A GEL COMPRISING A COPOLYMER, AND USEFUL COPOLYMERS | RHODIA CHIMIE SA (FR) | 2012-04-18 | — | — | EP | claimed |
| US-7884056-B2 | star block polymers comprising core and macromolecular branches; for controlling formation of viscoelastic gels | RHODIA CHIMIE (FR) | 2011-02-08 | — | — | US | claimed |
| US-7737237-B2 | Controlled structure copolymer comprising an amphoteric or zwitterionic part | PHODIA CHIMIE (FR) | 2010-06-15 | — | — | US | claimed |
| US-20100120637-A1 | Composition That Can Form a Gel Comprising a Copolymer, and Useful Copolymers | RHODIA CHIMIE (FR) | 2010-05-13 | — | — | US | claimed |
| US-20100004152-A1 | Synthetic Microgel Polymer Compositions for Treating and/or Modifying Hard Surfaces | RHODIA OPERATIONS (FR) | 2010-01-07 | — | — | US | claimed |
| US-20060217285-A1 | Controlled structure copolymer comprising an amphoteric or zwitterionic part | RHODIA CHIMIE (FR) | 2006-09-28 | — | — | US | claimed |
| US-20050276947-A1 | Package structure of organic electroluminescent device and package method thereof | RITDISPLAY CORPORATION (TW) | 2005-12-15 | — | — | US | claimed |
| CN-1705414-A | Sealing structure of organic electroluminescent device and its manufacturing process | RITDISPLAY CORP (CN) | 2005-12-07 | — | — | CN | claimed |