Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL3681377 | 1.00 | TGFBR1 (0.36) | TGFBR1ALDH1A1THRB | |
| SCHEMBL3820492 | 0.95 | TGFBR1 (0.39) | TGFBR1ALDH1A1THRB | |
| Trimethylammonium SCHEMBL866268 | 0.87 | NPC1 (0.35) | TGFBR1ALDH1A1 | |
| Trimethylammonium SCHEMBL148949 | 0.87 | NPC1 (0.35) | TGFBR1ALDH1A1 | |
| Trimethylammonium SCHEMBL444000 | 0.85 | TGFBR1 (0.41) | TGFBR1ALDH1A1THRB | |
| Trimethylammonium SCHEMBL1707073 | 0.84 | ACHE (0.41) | — | |
| Trimethylammonium SCHEMBL28049014 | 0.83 | TGFBR1 (0.39) | TGFBR1ALDH1A1THRB | |
| Trimethylammonium SCHEMBL869214 | 0.83 | TGFBR1 (0.39) | TGFBR1ALDH1A1THRB | |
| Trimethylammonium SCHEMBL176133 | 0.83 | TGFBR1 (0.39) | TGFBR1ALDH1A1THRB | |
| Trimethylammonium SCHEMBL895151 | 0.83 | TGFBR1 (0.39) | TGFBR1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070137781-A1 | PACKAGE METHOD OF ORGANIC ELECTROLUMINESCENT DEVICE | HUANG PING-TSUNG | 2007-06-21 | — | — | US | claimed |
| US-20050276947-A1 | Package structure of organic electroluminescent device and package method thereof | RITDISPLAY CORPORATION (TW) | 2005-12-15 | — | — | US | claimed |
| US-20070137781-A1 | PACKAGE METHOD OF ORGANIC ELECTROLUMINESCENT DEVICE | HUANG PING-TSUNG | 2007-06-21 | — | — | US | disclosed |
| US-20050276947-A1 | Package structure of organic electroluminescent device and package method thereof | RITDISPLAY CORPORATION (TW) | 2005-12-15 | — | — | US | disclosed |