Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL5454852 | 1.00 | TGFBR1 (0.36) | TGFBR1ALDH1A1THRB | |
| SCHEMBL3820492 | 0.95 | TGFBR1 (0.39) | TGFBR1ALDH1A1THRB | |
| Trimethylammonium SCHEMBL866268 | 0.87 | NPC1 (0.35) | TGFBR1ALDH1A1 | |
| Trimethylammonium SCHEMBL148949 | 0.87 | NPC1 (0.35) | TGFBR1ALDH1A1 | |
| Trimethylammonium SCHEMBL444000 | 0.85 | TGFBR1 (0.41) | TGFBR1ALDH1A1THRB | |
| Trimethylammonium SCHEMBL1707073 | 0.84 | ACHE (0.41) | — | |
| Trimethylammonium SCHEMBL28049014 | 0.83 | TGFBR1 (0.39) | TGFBR1ALDH1A1THRB | |
| Trimethylammonium SCHEMBL869214 | 0.83 | TGFBR1 (0.39) | TGFBR1ALDH1A1THRB | |
| Trimethylammonium SCHEMBL176133 | 0.83 | TGFBR1 (0.39) | TGFBR1ALDH1A1THRB | |
| Trimethylammonium SCHEMBL895151 | 0.83 | TGFBR1 (0.39) | TGFBR1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582733-B1 | POLYMERS COMPRISING SACCHARIDE SIDE GROUPS AND USE THEREOF | BASF SE (DE) | 2014-06-04 | — | — | EP | disclosed |
| US-7662871-B2 | Aqueous polymer dispersions, based on copolymers of vinyl aromatics and butadiene, method for their production and their use as sizing agents for paper | BASF AKTIENGESELLSCHAFT (DE) | 2010-02-16 | — | — | US | disclosed |
| EP-0972110-B2 | METHOD FOR PRODUCING HIGH DRY-STRENGTH PAPER, PULPBOARD AND CARDBOARD | BASF SE (DE) | 2009-03-11 | — | — | EP | disclosed |
| US-7074750-B2 | Treatment method, which promotes the removal of dirt, for the surfaces of textiles and non-textiles | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-11 | — | — | US | disclosed |
| EP-1287104-B1 | USE OF CATIONICALLY MODIFIED, PARTICLE-SHAPED, HYDROPHOBIC POLYMERS AS ADDITION AGENTS IN TEXTILE RINSING OR CARE PRODUCTS AND AS ADDITION AGENTS IN DETERGENTS | BASF AG (DE) | 2006-05-24 | — | — | EP | disclosed |
| EP-1501880-B1 | AQUEOUS POLYMER DISPERSIONS, BASED ON COPOLYMERS OF VINYL AROMATICS AND BUTADIENE, METHOD FOR THEIR PRODUCTION AND THEIR USE AS SIZING AGENTS FOR PAPER | BASF AG (DE) | 2006-02-15 | — | — | EP | disclosed |
| EP-1328573-B1 | HYDROPHILIC, OPEN-CELL, ELASTIC FOAMS WITH A MELAMINE/FORMALDEHYDE RESIN BASE, PRODUCTION THEREOF AND USE THEREOF IN HYGIENE PRODUCTS | BASF AG (DE) | 2005-11-09 | — | — | EP | disclosed |
| US-20050176878-A1 | Aqueous polymer dispersions, based on copolymers of vinyl aromatics and butadiene, method for their production and their use as sizing agents for paper | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-11 | — | — | US | disclosed |
| US-20050153865-A1 | Cationically modified, anionic polyurethane dispersions | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-14 | — | — | US | disclosed |
| US-6908490-B2 | Use of cationically modified, particle-shaped, hydrophobic polymers as addition agents in textile rinsing or care products and as addition agents in detergents | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-21 | — | — | US | disclosed |
| EP-0972110-A1 | METHOD FOR PRODUCING HIGH DRY-STRENGTH PAPER, PULPBOARD AND CARDBOARD | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-19 | — | — | EP | disclosed |
| EP-0952988-A1 | POLYMER-MODIFIED ANIONIC STARCH, METHOD FOR ITS PRODUCTION, AND ITS USE | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-03 | — | — | EP | disclosed |
| EP-0951505-A1 | POLYMER-MODIFIED STARCH, METHOD FOR ITS PRODUCTION, AND ITS USE | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-27 | — | — | EP | disclosed |
| US-5851300-A | Cationic modification of starch and use of the cationically modified starch | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| WO-1998045536-A1 | METHOD FOR PRODUCING HIGH DRY-STRENGTH PAPER, PULPBOARD AND CARDBOARD | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-15 | — | — | WO | disclosed |
| EP-0788516-B1 | CATIONIC MODIFICATION PROCESS FOR STARCH AND USE OF CATIONICALLY MODIFIED STARCH | BASF AG (DE) | 1998-07-29 | — | — | EP | disclosed |
| WO-1998031711-A1 | POLYMER-MODIFIED ANIONIC STARCH, METHOD FOR ITS PRODUCTION, AND ITS USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-07-23 | — | — | WO | disclosed |
| WO-1998031740-A1 | POLYMER-MODIFIED STARCH, METHOD FOR ITS PRODUCTION, AND ITS USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-07-23 | — | — | WO | disclosed |
| EP-0788516-A1 | CATIONIC MODIFICATION PROCESS FOR STARCH AND USE OF CATIONICALLY MODIFIED STARCH | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996013525-A1 | CATIONIC MODIFICATION PROCESS FOR STARCH AND USE OF CATIONICALLY MODIFIED STARCH | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-09 | — | — | WO | disclosed |