Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 7/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15846659 | 0.95 | ACHE (0.44) | ACHEEPHX1HTTMEN1KMT2A | |
| Trimethylammonium SCHEMBL866268 | 0.91 | NPC1 (0.35) | EPHX1CA12CA14 | |
| Trimethylammonium SCHEMBL148949 | 0.91 | NPC1 (0.35) | EPHX1CA12CA14 | |
| SCHEMBL16114711 | 0.85 | EPHX1 (0.36) | ACHEEPHX1KMT2ACA12CA14 | |
| Sulfuric Acid SCHEMBL3381903 | 0.85 | EPHX1 (0.48) | ACHEEPHX1HTTMEN1KMT2A | |
| SCHEMBL127975 | 0.85 | KDM4E (0.46) | — | |
| Trimethylammonium SCHEMBL5454852 | 0.84 | TGFBR1 (0.36) | — | |
| Trimethylammonium SCHEMBL3681377 | 0.84 | TGFBR1 (0.36) | — | |
| Water SCHEMBL28888819 | 0.84 | KDM4E (0.44) | — | |
| SCHEMBL15845800 | 0.83 | ACHE (0.42) | ACHEEPHX1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071462-A1 | ARTICLES COMPRISING AN OIL CAPTURE POLYMER | THE PROCTER & GAMBLE COMPANY (US) | 2018-04-19 | — | — | WO | claimed |
| US-20180100250-A1 | Articles Comprising an Oil Capture Polymer | THE PROCTER & GAMBLE COMPANY | 2018-04-12 | — | — | US | claimed |
| EP-1558658-B1 | CONTROLLED STRUCTURE COPOLYMER COMPRISING AN AMPHOTERIC OR ZWITTERIONIC PART | RHODIA CHIMIE SA (FR) | 2012-12-19 | — | — | EP | claimed |
| EP-1838762-B1 | COMPOSITION THAT CAN FORM A GEL COMPRISING A COPOLYMER, AND USEFUL COPOLYMERS | RHODIA CHIMIE SA (FR) | 2012-04-18 | — | — | EP | claimed |
| US-20060217285-A1 | Controlled structure copolymer comprising an amphoteric or zwitterionic part | RHODIA CHIMIE (FR) | 2006-09-28 | — | — | US | claimed |