SCHEMBL1490225

SCHEMBL1490225

O=S(=O)(F)c1cc[c]cc1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.41
TMPRSS4 Q9NRS4 2/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11574176 0.78 TSHR (0.56) F2TMPRSS4TP53CYP1A2CYP2D6
SCHEMBL818508 0.77 HTR6 (0.50) TSHR
SCHEMBL20194 0.72 ENPP2 (0.50)
Water SCHEMBL28012117 0.72 TSHR (0.55) CYP2D6TSHR
SCHEMBL27747701 0.72
SCHEMBL600074 0.72 ALDH1A1 (0.55)
SCHEMBL1726649 0.72
SCHEMBL19880 0.72 CA2 (0.55) TSHR
SCHEMBL50583 0.72 TSHR (0.55) CYP2D6TSHR
SCHEMBL1727552 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475282-B1 [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES WITH AFFINITY FOR THE TYPE-2 CANNABINOID RECEPTOR HOFFMANN LA ROCHE (CH) 2023-08-09 EP claimed
CN-114188606-B Electrolyte and application thereof 傲普(上海)新能源有限公司 2023-04-21 CN claimed
CN-115093418-A [1,2,3] triazolo [4,5-d ] pyrimidine derivatives having affinity for cannabinoid type 2 receptors 豪夫迈·罗氏有限公司 2022-09-23 CN claimed
CN-115073476-A [1,2,3] triazolo [4,5-d ] pyrimidine derivatives having affinity for cannabinoid type 2 receptors 豪夫迈·罗氏有限公司 2022-09-20 CN claimed
CN-114583278-A Low-temperature electrolyte of lithium ion battery and lithium ion battery 傲普(上海)新能源有限公司 2022-06-03 CN claimed
CN-114552012-A High-temperature high-rate electrolyte and lithium battery 傲普(上海)新能源有限公司 2022-05-27 CN claimed
CN-114497703-A High-temperature electrolyte and lithium battery 傲普(上海)新能源有限公司 2022-05-13 CN claimed
CN-114373989-A Electrolyte and application thereof 傲普(上海)新能源有限公司 2022-04-19 CN claimed
CN-114243112-A Flame-retardant electrolyte and application thereof 傲普(上海)新能源有限公司 2022-03-25 CN claimed
CN-114188606-A Electrolyte and application thereof 傲普(上海)新能源有限公司 2022-03-15 CN claimed
CN-100556931-C The dielectric film of branching sulphonated multiblock thing and this branching sulphonated multiblock thing of use LG CHEMICAL LTD (KR) 2009-11-04 CN claimed
CN-1898293-A Branched sulfonated multiblock copolymer and electrolyte membrane using the same LG CHEMICAL LTD (KR) 2007-01-17 CN claimed
CN-1089099-C Monoazo dyes substituted by haloalkylacarbamate and sulphonylfluoride group BASF AG (DE) 2002-08-14 CN claimed
US-5973127-A WATER INSOLUBILITY; COLORING SYNTHETIC TEXTILE FABRICS BASF AKTIENGESELLSCHAFT (DE) 1999-10-26 US claimed
CN-1225656-A Monoazo dyes substituted by haloalkyl carbamate and sulfonyl fluoride BASF AG (DE) 1999-08-11 CN claimed
US-5782934-A Process of dyeing with disazo dyes containing a fluorosulphonyl group and use thereof ZENECA LIMITED (GB) 1998-07-21 US claimed
EP-0740690-A1 MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF ZENECA LIMITED (GB) 1996-11-06 EP claimed
WO-1995020014-A1 MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF ZENECA LIMITED (GB) 1995-07-27 WO claimed
US-4115448-A Carbamylguanidine antimicrobial compounds COOPER LABORATORIES, INC. (US) 1978-09-19 US claimed
US-4022962-A DENTAL PLAQUE INHIBITORS COOPER LABORATORIES, INC. (US) 1977-05-10 US claimed