Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490943 | 0.81 | MEN1 (0.58) | SLC22A6SLC22A8MEN1RAB9AKMT2A | |
| SCHEMBL1490921 | 0.78 | P4HB (0.43) | APP | |
| SCHEMBL1490975 | 0.78 | EPHX2 (0.44) | RAB9AKMT2A | |
| SCHEMBL3648979 | 0.76 | HTT (0.61) | APPGCGRSLC22A6SLC22A8MEN1 | |
| SCHEMBL10322973 | 0.74 | APP (0.50) | APPGCGRSLC22A6SLC22A8MEN1 | |
| SCHEMBL3641624 | 0.74 | APP (0.50) | APPGCGRSLC22A6SLC22A8MEN1 | |
| SCHEMBL16061281 | 0.74 | HTT (0.55) | SLC22A6SLC22A8MEN1RAB9AKMT2A | |
| SCHEMBL10321468 | 0.72 | CA12 (0.59) | APPGCGRSLC22A6SLC22A8MEN1 | |
| SCHEMBL24436791 | 0.71 | APP (0.50) | APPGCGRSLC22A6SLC22A8MEN1 | |
| SCHEMBL2664110 | 0.71 | APP (0.54) | APPGCGRKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2477698-A2 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | Centre National de la Recherche Scientifique (FR) | 2012-07-25 | — | — | EP | disclosed |
| WO-2011033115-A2 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-03-24 | — | — | WO | disclosed |