Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179119 | 0.78 | KDM4E (0.43) | FDPSKDM4EKMT2ATDP1MEN1 | |
| SCHEMBL11846183 | 0.70 | FDPS (0.44) | FDPSKDM4EKMT2ATDP1MAPT | |
| SCHEMBL122501 | 0.70 | KDM4E (0.41) | FDPSKDM4EKMT2AMEN1MAPT | |
| SCHEMBL1408791 | 0.70 | ALDH1A1 (0.39) | KDM4ETDP1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL2763850 | 0.69 | ALDH1A1 (0.35) | KDM4ETDP1L3MBTL1HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9544896 | 0.68 | FDPS (0.42) | FDPSKDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL1408982 | 0.67 | KDM4E (0.45) | KDM4EKMT2ATDP1MEN1MAPT | |
| SCHEMBL17988784 | 0.66 | MEN1 (0.38) | KDM4EKMT2ATDP1MEN1MAPT | |
| SCHEMBL2460600 | 0.66 | ALDH1A1 (0.37) | KDM4EKMT2ATDP1MEN1MAPT | |
| SCHEMBL11443712 | 0.64 | SIGMAR1 (0.38) | KDM4EKMT2ATDP1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9186349-B2 | Diaza heterocyclic compounds for phototherapy | MALLINCKRODT LLC (US) | 2015-11-17 | — | — | US | disclosed |
| US-20120058954-A1 | Diaza Heterocyclic Compounds for Phototherapy | OCERA THERAPEUTICS LLC | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058954-A1 | Diaza Heterocyclic Compounds for Phototherapy | BAD, BID, CASP3 | FDPS 1964/4885KDM4E 870/4885KMT2A 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.