Sugi Predict

Sugi Predict / Compounds / SCHEMBL1491236

SCHEMBL1491236

SCHEMBL1491236

O=S(=O)(Cl)c1ccccc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 5/20 0.44
▸ ALDH1A1 P00352 4/20 0.44
▸ HSD17B10 Q99714 2/20 0.44
▸ CDK2 P24941 1/20 0.43
▸ CA2 P00918 3/20 0.43
▸ CA4 P22748 3/20 0.43
▸ POLB P06746 2/20 0.43
▸ CA12 O43570 2/20 0.43
▸ CA5A P35218 2/20 0.43
▸ CA14 Q9ULX7 2/20 0.43
▸ CA5B Q9Y2D0 2/20 0.43
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ GMNN O75496 1/20 0.43
▸ EGFR P00533 1/20 0.43
▸ LMNA P02545 1/20 0.43
▸ FYN P06241 1/20 0.43
▸ CA3 P07451 1/20 0.43
▸ CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30013888 1.00 TDP1 (0.44) TDP1ALDH1A1HSD17B10CDK2CA2
SCHEMBL1491272 0.81 ALDH1A1 (0.48) TDP1ALDH1A1HSD17B10CDK2CA2
SCHEMBL250199 0.81 ALDH1A1 (0.55) TDP1ALDH1A1HSD17B10CA2CA4
SCHEMBL11413280 0.79 CDK2 (0.44) TDP1ALDH1A1HSD17B10CDK2CA2
SCHEMBL11149914 0.79 CA2 (0.47) TDP1ALDH1A1HSD17B10CDK2CA2
SCHEMBL29381412 0.79 TDP1 (0.50) TDP1ALDH1A1HSD17B10CDK2CA2
SCHEMBL18837 0.79 TDP1 (0.50) TDP1ALDH1A1HSD17B10CDK2CA2
SCHEMBL190005 0.79 TDP1 (0.50) TDP1ALDH1A1HSD17B10CDK2CA2
Catechol SCHEMBL1491270 0.78 ALDH1A1 (0.62) TDP1ALDH1A1HSD17B10CDK2CA2
SCHEMBL899804 0.78 CDK2 (0.68) TDP1ALDH1A1HSD17B10CDK2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110658137-B Combined measurement method for measuring contents of niobium and phosphorus in ferrocolumbium 广东韶钢松山股份有限公司 2022-06-10 — — CN claimed
CN-112697732-B Method for detecting niobium content in alloy 攀钢集团江油长城特殊钢有限公司 2022-05-03 — — CN claimed
CN-112697732-A Method for detecting niobium content in alloy 攀钢集团江油长城特殊钢有限公司 2021-04-23 — — CN claimed
CN-110658137-A Combined measurement method for measuring niobium and phosphorus content in ferrocolumbium 广东韶钢松山股份有限公司 2020-01-07 — — CN claimed
US-6727359-B2 REACTING PHENOXIDE SULFONYLCHLORIDE AND ACETOACETAMIDE-N-SULFONYL PHENOXIDE AND AMMONIA USING CATALYST BDL CORPORATION 2004-04-27 — — US claimed
US-20030065172-A1 Composition comprising 6-methyl-3,4dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide, its salts, preparation thereof and uses therefor BDL CORPORATION 2003-04-03 — — US claimed
US-11787837-B2 DCHBS-active esters of PEG compounds and their use NOVO NORDISK A/S (DK) 2023-10-17 — — US disclosed
CN-109922835-B DCHBS active ester of PEG compound and application thereof 诺和诺德股份有限公司 2023-08-04 — — CN disclosed
US-20230022304-A1 WDR5-MYC INHIBITORS VANDERBILT UNIVERSITY 2023-01-26 — — US disclosed
CN-110658137-B Combined measurement method for measuring contents of niobium and phosphorus in ferrocolumbium 广东韶钢松山股份有限公司 2022-06-10 — — CN disclosed
CN-110658137-B Combined measurement method for measuring contents of niobium and phosphorus in ferrocolumbium 广东韶钢松山股份有限公司 2022-06-10 — — CN disclosed
CN-112697732-B Method for detecting niobium content in alloy 攀钢集团江油长城特殊钢有限公司 2022-05-03 — — CN disclosed
CN-113916875-A Method for determining element niobium in high-temperature alloy 中国航发北京航空材料研究院 2022-01-11 — — CN disclosed
US-4861913-A Bicyclic sulfonamide derivatives SHIONOGI & CO., LTD. (JP) 1989-08-29 — — US disclosed
EP-0226346-A1 Bicyclic sulfonamide derivatives SHIONOGI & CO., LTD. (JP) 1987-06-24 — — EP disclosed
EP-0061071-B1 ACTIVATED APOGLUCOSE OXIDASE, METHOD OF PREPARING IT, ITS USE IN SPECIFIC BINDING ASSAY METHODS AND REAGENT MEANS AND TEST KITS CONTAINING IT MILES LABORATORIES, INC. (US) 1985-05-29 — — EP disclosed
US-4443536-A CONTAINING BALLAST WITH HYDROXYPHENYLSULFINYL OR HYDROXYPHENYLSULFONYL GROUP EASTMAN KODAK COMPANY (US) 1984-04-17 — — US disclosed
US-4388246-A THERMAL SPLITTING OF CARBAMATES BAYER AKTIENGESELLSCHAFT (DE) 1983-06-14 — — US disclosed
EP-0073636-A1 Photographic elements containing ballasted couplers EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-03-09 — — EP disclosed
EP-0061013-A1 Process for the preparation of polyisocyanates BAYER AG (DE) 1982-09-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065172-A1 Composition comprising 6-methyl-3,4dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide, its salts, preparation thereof and uses therefor PDXK, ITK, KHK TDP1 4639/4885ALDH1A1 636/4885HSD17B10 1156/4885
US-20230022304-A1 WDR5-MYC INHIBITORS MYC, WDR5, MYCBP TDP1 3147/4885ALDH1A1 3982/4885HSD17B10 3101/4885
US-11787837-B2 DCHBS-active esters of PEG compounds and their use HBB, IAPP, GLP1R TDP1 4759/4885ALDH1A1 4448/4885HSD17B10 549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.