Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14919971 | 0.83 | PLAU (0.39) | SLC6A3SLC6A4SLC6A2MAOAMAOB | |
| SCHEMBL16197589 | 0.74 | SLC6A4 (0.34) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL14920371 | 0.71 | MAOA (0.38) | SLC6A3SLC6A4SLC6A2NOS3NOS1 | |
| SCHEMBL31446629 | 0.69 | RAB9A (0.40) | P2RX7 | |
| SCHEMBL12614852 | 0.67 | NOS3 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL31368996 | 0.67 | SLC6A3 (0.46) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL31368804 | 0.67 | SLC6A3 (0.46) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL14934983 | 0.66 | SLC6A3 (0.46) | SLC6A3SLC6A4SLC6A2MAOAMAOB | |
| SCHEMBL15999649 | 0.66 | NOS3 (0.34) | NOS3NOS1NOS2TAAR1 | |
| SCHEMBL118541 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013064521-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-05-10 | — | — | WO | disclosed |