Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14925914 | 0.82 | ALDH1A1 (0.32) | HPGD | |
| SCHEMBL14925929 | 0.63 | NAMPT (0.33) | ADRA1DADRA1AADRA1BSPRALOX5 | |
| SCHEMBL16545971 | 0.63 | KMT2A (0.51) | HPGDTDP1 | |
| SCHEMBL14518464 | 0.62 | HDAC4 (0.51) | HDAC4HPGDTDP1NAMPT | |
| SCHEMBL11910533 | 0.62 | TRPM8 (0.33) | ADRA1DADRA1AADRA1BSPRALOX5 | |
| SCHEMBL21004417 | 0.62 | SPR (0.44) | SPRALOX5PTGS1PTGS2TRPM8 | |
| SCHEMBL24941110 | 0.61 | SIRT3 (0.54) | ADRA1DADRA1AADRA1BSPRKDM5A | |
| SCHEMBL328097 | 0.61 | DAO (0.52) | TRPM8HDAC4HPGDTDP1 | |
| SCHEMBL6203474 | 0.61 | ALOX5 (0.37) | ADRA1DADRA1AADRA1BALOX5PTGS1 | |
| SCHEMBL13758037 | 0.61 | MMP13 (0.49) | HDAC4HPGDTDP1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9247745-B2 | Substituted pyridazines for controlling invertebrate pests | BASF SE (DE) | 2016-02-02 | — | — | US | disclosed |
| US-20130116264-A1 | Novel Hetaryl (thio)carboxamide Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116264-A1 | Novel Hetaryl (thio)carboxamide Compounds for Controlling Invertebrate Pests | TH, CYP8B1, ETFA | ADRA1D 2569/4885ADRA1A 1458/4885ADRA1B 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.