SCHEMBL14926786

SCHEMBL14926786

CC1COC(c2cc(F)c(C(F)(F)Oc3ccc(-c4cc(F)c(F)c(F)c4)c(F)c3)c(F)c2)OC1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 2/20 0.36
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
CETP P11597 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17177805 0.97 GRM2 (0.36) GRM2ALOX5APFEN1CETP
SCHEMBL21374508 0.94 GRM2 (0.34) GRM2ALOX5APFEN1
SCHEMBL15497674 0.94 GRM2 (0.32) GRM2
SCHEMBL16710254 0.94 GRM2 (0.36) GRM2ALOX5APFEN1
SCHEMBL16167874 0.91 GRM2 (0.39) GRM2ALOX5APFEN1
SCHEMBL20275802 0.90 GRM2 (0.38) GRM2ALOX5APFEN1
SCHEMBL16710255 0.89 GRM2 (0.34) GRM2ALOX5APFEN1
SCHEMBL20275807 0.89 GRM2 (0.35) GRM2ALOX5APFEN1CETP
SCHEMBL14888020 0.89 GRM2 (0.35) GRM2ALOX5APFEN1CETP
SCHEMBL17033202 0.88 GRM2 (0.33) GRM2ALOX5APFEN1CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200299581-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL COMPOSITION AND OPTICAL SWITCHING DEVICE USING SAME JNC CORPORATION (JP) 2020-09-24 US disclosed
US-10633589-B2 Liquid crystal medium, optical device and liquid crystal compound JNC CORPORATION (JP) 2020-04-28 US disclosed
US-20190316036-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC CORPORATION (JP) 2019-10-17 US disclosed
EP-2586764-B1 COMPOUND HAVING BRANCHED ALKYL OR BRANCHED ALKENYL, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL ELEMENT JNC CORP (JP) 2019-09-18 EP disclosed
US-10308870-B2 Liquid crystal medium, optical device and liquid crystal compound JNC CORPORATION (JP) 2019-06-04 US disclosed
US-20180112131-A1 LIQUID CRYSTAL MEDIUM, OPTICAL DEVICE AND LIQUID CRYSTAL COMPOUND JNC CORPORATION (JP) 2018-04-26 US disclosed
US-9738831-B2 Optically isotropic liquid crystal composition and optical device JNC CORPORATION (JP) 2017-08-22 US disclosed
US-9738831-B2 Optically isotropic liquid crystal composition and optical device JNC CORPORATION (JP) 2017-08-22 US disclosed
US-9611429-B2 Liquid crystal medium, optical device and liquid crystal compound JNC CORPORATION (JP) 2017-04-04 US disclosed
US-9611429-B2 Liquid crystal medium, optical device and liquid crystal compound JNC CORPORATION (JP) 2017-04-04 US disclosed
US-9593094-B2 Liquid crystal medium, optical device, and liquid crystal compound JNC CORPORATION (JP) 2017-03-14 US disclosed
US-20160304784-A1 LIQUID CRYSTAL MEDIUM, OPTICAL DEVICE AND LIQUID CRYSTAL COMPOUND JNC CORPORATION (JP) 2016-10-20 US disclosed
US-20160122648-A1 LIQUID CRYSTAL MEDIUM, OPTICAL DEVICE AND LIQUID CRYSTAL COMPOUND JNC CORPORATION (JP) 2016-05-05 US disclosed
US-20160122648-A1 LIQUID CRYSTAL MEDIUM, OPTICAL DEVICE AND LIQUID CRYSTAL COMPOUND JNC CORPORATION (JP) 2016-05-05 US disclosed
US-20160002536-A1 LIQUID CRYSTAL MEDIUM, OPTICAL DEVICE, AND LIQUID CRYSTAL COMPOUND JNC PETROCHEMICAL CORPORATION (JP) 2016-01-07 US disclosed
US-20150240159-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL COMPOSITION AND OPTICAL DEVICE JNC CORPORATION (JP) 2015-08-27 US disclosed
US-20150240159-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL COMPOSITION AND OPTICAL DEVICE JNC CORPORATION (JP) 2015-08-27 US disclosed
US-20150129800-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2015-05-14 US disclosed
US-20130114009-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-05-09 US disclosed
US-20130114009-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10308870-B2 Liquid crystal medium, optical device and liquid crystal compound OCIAD1, HCN3, HCN1 GRM2 2308/4885ALOX5AP 2798/4885FEN1 3182/4885
US-20160002536-A1 LIQUID CRYSTAL MEDIUM, OPTICAL DEVICE, AND LIQUID CRYSTAL COMPOUND HCN1, HCN3, HCN2 GRM2 2151/4885ALOX5AP 1630/4885FEN1 2132/4885
US-20150129800-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY CCND2, CFD, CRY1 GRM2 2026/4885ALOX5AP 2885/4885FEN1 4353/4885
US-20150240159-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL COMPOSITION AND OPTICAL DEVICE SCO2, CNOT1, LEO1 GRM2 1980/4885ALOX5AP 456/4885FEN1 1516/4885
US-20160304784-A1 LIQUID CRYSTAL MEDIUM, OPTICAL DEVICE AND LIQUID CRYSTAL COMPOUND HCN1, PIEZO1, NCS1 GRM2 1606/4885ALOX5AP 2522/4885FEN1 2590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.