SCHEMBL14933684

SCHEMBL14933684

O=Cc1cc(C(=O)Cl)cc(C(=O)Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
UNG P13051 1/20 0.43
ALDH1A1 P00352 6/20 0.39
KDM4E B2RXH2 1/20 0.34
PTGS2 P35354 1/20 0.34
RAB9A P51151 1/20 0.34
TRIM24 O15164 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALDH5A1 P51649 1/20 0.33
ABAT P80404 1/20 0.33
TSHR P16473 1/20 0.31
XDH P47989 1/20 0.31
SRC P12931 1/20 0.31
PARP10 Q53GL7 1/20 0.31
PARP3 Q9Y6F1 1/20 0.31
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28457775 0.95 UNG (0.43) UNGALDH1A1KDM4EPTGS2RAB9A
SCHEMBL8979359 0.87 TPMT (0.41) UNGALDH1A1RAB9AHSD17B10
SCHEMBL8979335 0.85 TPMT (0.40) UNGALDH1A1HSD17B10SRCCYP2A6
SCHEMBL38576 0.81 ALDH1A1 (0.40) ALDH1A1TSHR
Hydrochloric Acid SCHEMBL18918955 0.78 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL1902705 0.78 UNG (0.68) UNGALDH1A1KDM4EPTGS2RAB9A
SCHEMBL3470017 0.77 UNG (0.61) UNGALDH1A1KDM4ETRIM24TRIM33
Benzene SCHEMBL28576976 0.75 TDP1 (0.43) ALDH1A1HSD17B10TSHR
SCHEMBL29201943 0.75 ALDH1A1 (0.37) ALDH1A1TSHR
Ethane SCHEMBL29138437 0.75 ALDH1A1 (0.37) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11684897-B2 Titania-polyamide nanocomposite formed by in situ polymerization KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-06-27 US disclosed
US-11642630-B2 Method for removing a contaminant from water with a titanium polyamide nanocomposite KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-05-09 US disclosed
US-20220401891-A1 METHOD FOR REMOVING A CONTAMINANT FROM WATER WITH A TITANIUM POLYAMIDE NANOCOMPOSITE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2022-12-22 US disclosed
US-20220401890-A1 TITANIA-POLYAMIDE NANOCOMPOSITE FORMED BY IN SITU POLYMERIZATION KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2022-12-22 US disclosed
US-20150274639-A1 METHODS OF USE FOR COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE CURZA GLOBAL, LLC 2015-10-01 US disclosed
US-20150274639-A1 METHODS OF USE FOR COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE CURZA GLOBAL, LLC 2015-10-01 US disclosed
WO-2013066453-A1 COMPOUNDS CAPABLE OF UNDERGOING SYMMETRY BREAKING INTRAMOLECULAR CHARGE TRANSFER IN A POLARIZING MEDIUM AND ORGANIC PHOTOVOLTAIC DEVICES COMPRISING THE SAME UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2013-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150274639-A1 METHODS OF USE FOR COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE SRM, SMOX, SMS UNG 27/4885ALDH1A1 2333/4885KDM4E 1709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.