Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 1.00 |
| ▸ | MAOB | P27338 | 4/20 | 0.74 |
| ▸ | MAOA | P21397 | 2/20 | 0.74 |
| ▸ | ACHE | P22303 | 6/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5356129 | 0.79 | MAOB (0.71) | ABCB1MAOBMAOAACHEAPP | |
| SCHEMBL813820 | 0.79 | MAOB (0.71) | ABCB1MAOBMAOAACHEAPP | |
| SCHEMBL14937328 | 0.73 | ABCB1 (1.00) | ABCB1 | |
| SCHEMBL14937330 | 0.73 | ABCB1 (1.00) | ABCB1 | |
| SCHEMBL2502424 | 0.72 | TXNRD1 (0.65) | ABCB1APP | |
| SCHEMBL23761627 | 0.72 | ABCB1 (0.67) | ABCB1 | |
| SCHEMBL6961773 | 0.71 | MAOB (0.74) | ABCB1MAOBMAOAACHEAPP | |
| SCHEMBL6961770 | 0.71 | MAOB (0.74) | ABCB1MAOBMAOAACHEAPP | |
| SCHEMBL31501134 | 0.70 | MAOB (0.73) | ABCB1MAOBMAOAACHEAPP | |
| SCHEMBL5428973 | 0.70 | CYP1A2 (0.67) | ABCB1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MEDIZINISCHE UNIVERSITAT WIEN (AT) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MALT1, VHL, ETV6 | ABCB1 19/4885MAOB 3578/4885MAOA 4115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.