Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940301 | 0.93 | SIGMAR1 (0.55) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL14939907 | 0.91 | SIGMAR1 (0.55) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL14939908 | 0.90 | SIGMAR1 (0.51) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL14939036 | 0.89 | NPSR1 (0.47) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL14938846 | 0.86 | ALDH1A1 (0.41) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL14939377 | 0.86 | SIGMAR1 (0.54) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL14939844 | 0.86 | NPSR1 (0.45) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL14940465 | 0.85 | SIGMAR1 (0.50) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL14939017 | 0.85 | HTR7 (0.48) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL14939761 | 0.84 | NPSR1 (0.61) | SIGMAR1DRD2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |