Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | USP1 | O94782 | 10/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944715 | 0.90 | TLR7 (0.41) | ADORA1TLR7USP1LMNAHCRTR1 | |
| SCHEMBL20343814 | 0.89 | USP1 (0.37) | ADORA1TLR7USP1ALDH1A1CYP3A4 | |
| SCHEMBL14944722 | 0.75 | USP1 (0.34) | ADORA1TLR7USP1HCRTR1HCRTR2 | |
| SCHEMBL14944614 | 0.69 | TLR7 (0.51) | ADORA1TLR7 | |
| SCHEMBL14944647 | 0.68 | TLR7 (0.41) | TLR7HTT | |
| SCHEMBL20343751 | 0.63 | PNP (0.38) | TLR7ALDH1A1CYP3A4HPGD | |
| SCHEMBL20343831 | 0.63 | HPGD (0.38) | TLR7ALDH1A1CYP3A4HPGD | |
| SCHEMBL28079351 | 0.62 | LMNA (0.61) | CYP11B1CYP11B2LMNAHCRTR1HCRTR2 | |
| SCHEMBL14987117 | 0.62 | HTT (0.63) | CYP11B1CYP11B2LMNAHTTALDH1A1 | |
| SCHEMBL20343784 | 0.61 | DRD2 (0.39) | TLR7HTTALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068438-A1 | PURINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN R&D IRELAND (IE) | 2013-05-16 | — | — | WO | disclosed |