Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.60 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14946490 | 0.84 | RIPK1 (0.60) | RIPK1AOC3MEN1KMT2AALDH1A1 | |
| SCHEMBL17278345 | 0.80 | RIPK1 (0.61) | RIPK1AOC3MEN1KMT2AALDH1A1 | |
| SCHEMBL29565507 | 0.80 | RIPK1 (0.65) | RIPK1AOC3MEN1KMT2AALDH1A1 | |
| SCHEMBL9824208 | 0.76 | RIPK1 (0.64) | RIPK1AOC3ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL25711795 | 0.76 | RIPK1 (0.59) | RIPK1AOC3MEN1KMT2AALDH1A1 | |
| SCHEMBL14946457 | 0.75 | HSD11B1 (0.51) | AOC3MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL17882179 | 0.75 | RIPK1 (1.00) | RIPK1AOC3GAA | |
| SCHEMBL18773018 | 0.73 | RIPK1 (0.53) | RIPK1AOC3MEN1KMT2AKDM4E | |
| SCHEMBL14540715 | 0.73 | RIPK1 (0.59) | RIPK1AOC3MEN1KMT2AALDH1A1 | |
| SCHEMBL14946473 | 0.72 | ALDH1A1 (0.65) | MEN1KMT2AKDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170367340-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2017-12-28 | — | — | US | disclosed |
| US-9609870-B2 | Herbicidal isoxazolo[5,4-b]pyridines | BASF SE (DE) | 2017-04-04 | — | — | US | disclosed |
| US-9609870-B2 | Herbicidal isoxazolo[5,4-b]pyridines | BASF SE (DE) | 2017-04-04 | — | — | US | disclosed |
| US-20160037777-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2016-02-11 | — | — | US | disclosed |
| US-20160037777-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2016-02-11 | — | — | US | disclosed |
| US-9131695-B2 | Herbicidal isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9131695-B2 | Herbicidal isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2015-09-15 | — | — | US | disclosed |
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | RIPK1 4236/4885AOC3 892/4885MEN1 4689/4885 |
| US-20160037777-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | RIPK1 4236/4885AOC3 892/4885MEN1 4689/4885 |
| US-20170367340-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | RIPK1 4236/4885AOC3 892/4885MEN1 4689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.