SCHEMBL14947854

SCHEMBL14947854

CNCCCCC(NC=O)C(=O)NC

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 1/20 0.38
▸ ADH1B P00325 1/20 0.33
▸ ADH1C P00326 1/20 0.33
▸ ADH1A P07327 1/20 0.33
▸ ADH4 P08319 1/20 0.33
▸ ADH7 P40394 1/20 0.33
▸ CPB2 Q96IY4 1/20 0.33
▸ DPP7 Q9UHL4 1/20 0.31
▸ SIRT6 Q8N6T7 1/20 0.31
▸ SIRT1 Q96EB6 1/20 0.31
▸ GNAI3 P08754 1/20 0.30
▸ GNAO1 P09471 1/20 0.30
▸ GNAI1 P63096 1/20 0.30
▸ PAOX Q6QHF9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13350921 0.95 KISS1R (0.42) KISS1RADH1BADH1CADH1AADH4
SCHEMBL29330934 0.84 CPB2 (0.39) KISS1RADH1BADH1CADH1AADH4
SCHEMBL21975039 0.84 SIRT6 (0.39) KISS1RADH1BADH1CADH1AADH4
SCHEMBL13351138 0.83 ADH1B (0.53) ADH1BADH1CADH1AADH4ADH7
SCHEMBL13350892 0.83 ADH1B (0.53) ADH1BADH1CADH1AADH4ADH7
SCHEMBL22020398 0.83 KISS1R (0.34) KISS1RADH1BADH1CADH1AADH4
SCHEMBL13350786 0.82 SLC15A1 (0.43) ADH1BADH1CADH1AADH4ADH7
SCHEMBL13416823 0.82 KISS1R (0.42) KISS1RCPB2DPP7SIRT6SIRT1
SCHEMBL22838206 0.81 KISS1R (0.44) KISS1RADH1BADH1CADH1AADH4
SCHEMBL29347143 0.81 TSHR (0.31) ADH1BADH1CADH1AADH4ADH7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703907-B2 Controlled drug release from dendrimers PROLYNX LLC (US) 2014-04-22 — — US disclosed
US-20130123461-A1 CONTROLLED DRUG RELEASE FROM DENDRIMERS PROLYNX LLC (US) 2013-05-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130123461-A1 CONTROLLED DRUG RELEASE FROM DENDRIMERS SLC43A1, SLC47A1, SLC47A2 KISS1R 127/4885ADH1B 4325/4885ADH1C 4414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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