Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 4/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964291 | 0.87 | IDO1 (0.39) | ALOX15HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14462393 | 0.85 | ALOX15 (0.48) | ALOX15HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4984072 | 0.85 | IDO1 (0.36) | IDO1 | |
| SCHEMBL14964260 | 0.82 | EGFR (0.39) | CYP3A4CYP2D6CYP2C19ALDH1A1LMNA | |
| SCHEMBL14964279 | 0.82 | IDO1 (0.33) | IDO1 | |
| SCHEMBL4979731 | 0.82 | IDO1 (0.34) | ALDH1A1KMT2AMAPTLMNAL3MBTL1 | |
| SCHEMBL4900358 | 0.81 | ALOX15 (0.47) | ALOX15HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4727606 | 0.81 | ALOX15 (0.47) | ALOX15HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4980217 | 0.81 | TAAR1 (0.35) | CYP1A2CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL16581715 | 0.80 | TBXAS1 (0.34) | F2F10IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450351-B2 | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | INCYTE CORPORATION (US) | 2013-05-28 | — | — | US | claimed |