Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966204 | 0.92 | SLC2A1 (0.42) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL14969471 | 0.90 | KDM4E (0.41) | SUCNR1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL14965370 | 0.89 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL14965626 | 0.88 | LTA4H (0.40) | SUCNR1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL14965511 | 0.88 | LTA4H (0.40) | SUCNR1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL14965672 | 0.88 | DRD4 (0.47) | ALDH1A1MEN1KMT2AMCHR1 | |
| SCHEMBL14971109 | 0.87 | TP53 (0.40) | ALDH1A1LMNAMAPTSLC2A1 | |
| SCHEMBL14966243 | 0.87 | TNIK (0.45) | SUCNR1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL14966019 | 0.87 | MCHR1 (0.39) | HSP90AA1HSP90AB1MCHR1SLC2A1 | |
| SCHEMBL14965684 | 0.85 | CHKA (0.45) | SUCNR1ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |