SCHEMBL14966932

SCHEMBL14966932

O=C(Oc1ccccc1)C1OC12CCCCC2

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FAAH O00519 9/20 0.45
TRPV1 Q8NER1 8/20 0.43
POLB P06746 2/20 0.42
ELANE P08246 2/20 0.42
ALDH1A1 P00352 2/20 0.42
RAB9A P51151 1/20 0.42
KDM4E B2RXH2 1/20 0.42
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
AKR1C1 Q04828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967009 0.98 FAAH (0.43) FAAHTRPV1POLBELANEALDH1A1
SCHEMBL14967125 0.95 ALDH1A1 (0.41) FAAHTRPV1POLBELANEALDH1A1
SCHEMBL24111962 0.76 TSHR (0.45) ELANEALDH1A1KMT2ATDP1
SCHEMBL14968010 0.76 ALDH1A1 (0.42) POLBELANEALDH1A1RAB9AKDM4E
SCHEMBL14968285 0.75 ALDH1A1 (0.45) POLBELANEALDH1A1KDM4ETDP1
SCHEMBL16109691 0.74 ALDH1A1 (0.41) POLBELANEALDH1A1KDM4EHTT
SCHEMBL14967425 0.72 POLB (0.40) POLBELANEALDH1A1RAB9A
SCHEMBL14967544 0.70 ALDH1A1 (0.41) POLBELANEALDH1A1RAB9AKDM4E
SCHEMBL14967432 0.70 ELANE (0.38) POLBELANEALDH1A1KDM4EHTT
SCHEMBL22390232 0.69 CYP2C19 (0.32) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed