SCHEMBL14967392

SCHEMBL14967392

CC(C)OC(=O)C1(c2ccccc2)OC12CCCCC2

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
APOBEC3A P31941 3/20 0.44
APOBEC3G Q9HC16 3/20 0.44
AKR1C1 Q04828 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CHRM3 P20309 2/20 0.37
HDAC4 P56524 1/20 0.37
HTT P42858 1/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 1/20 0.36
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967459 0.99 APOBEC3A (0.45) APOBEC3AAPOBEC3GAKR1C1ALDH1A1CHRM3
SCHEMBL14967282 0.96 APOBEC3A (0.42) APOBEC3AAPOBEC3GAKR1C1ALDH1A1HTT
SCHEMBL14968058 0.89 ABHD10 (0.36) APOBEC3AAPOBEC3GALDH1A1SMN1; SMN2SLC6A2
SCHEMBL14968196 0.87 ABHD10 (0.37) APOBEC3AAPOBEC3GALDH1A1SMN1; SMN2
SCHEMBL14967683 0.85 SLC6A4 (0.48) ALDH1A1MAPK1SMN1; SMN2SLC6A4SLC6A3
SCHEMBL14967801 0.84 ABHD10 (0.37) ALDH1A1SMN1; SMN2
SCHEMBL14967505 0.84 MEN1 (0.45) APOBEC3AAPOBEC3GAKR1C1ALDH1A1CHRM3
SCHEMBL14967783 0.84 SLC6A4 (0.46) ALDH1A1MAPK1SMN1; SMN2SLC6A4SLC6A3
SCHEMBL14968268 0.82 MEN1 (0.46) APOBEC3AAPOBEC3GAKR1C1ALDH1A1CHRM3
SCHEMBL14967675 0.81 HPGD (0.43) ALDH1A1MAPK1SMN1; SMN2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed