SCHEMBL14967801

SCHEMBL14967801

Cc1ccc(C2(C(=O)OC(C)C)OC23CCC3)cc1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ABHD10 Q9NUJ1 1/20 0.37
OPRM1 P35372 1/20 0.35
ALDH1A1 P00352 4/20 0.34
MAPT P10636 4/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HPGD P15428 2/20 0.34
KDM4E B2RXH2 1/20 0.34
POLB P06746 1/20 0.33
METAP2 P50579 1/20 0.33
LMNA P02545 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
HTR1E P28566 1/20 0.32
S1PR3 Q99500 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
PKM P14618 1/20 0.32
CYP2C19 P33261 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14968196 0.97 ABHD10 (0.37) ABHD10OPRM1ALDH1A1MAPTSMN1; SMN2
SCHEMBL14968058 0.96 ABHD10 (0.36) ABHD10OPRM1ALDH1A1MAPTSMN1; SMN2
SCHEMBL14967282 0.89 APOBEC3A (0.42) ALDH1A1SMN1; SMN2HPGDLMNA
SCHEMBL14967675 0.88 HPGD (0.43) ALDH1A1MAPTSMN1; SMN2HPGDKDM4E
SCHEMBL14967459 0.86 APOBEC3A (0.45) ALDH1A1SMN1; SMN2POLBLMNA
SCHEMBL14967244 0.85 CYP3A4 (0.42) OPRM1ALDH1A1MAPTSMN1; SMN2HPGD
SCHEMBL14967783 0.85 SLC6A4 (0.46) ALDH1A1MAPTSMN1; SMN2HPGDKDM4E
SCHEMBL14967392 0.84 APOBEC3A (0.44) ALDH1A1SMN1; SMN2
SCHEMBL14967683 0.84 SLC6A4 (0.48) ALDH1A1MAPTSMN1; SMN2HPGDKDM4E
SCHEMBL14967200 0.83 OPRM1 (0.49) OPRM1ALDH1A1MAPTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed