SCHEMBL14967403

SCHEMBL14967403

CCC1(c2ccccc2)OC1C(=O)OC(C)C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
HCAR3 P49019 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
MAPT P10636 2/20 0.35
APOBEC3A P31941 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
PYGM P11217 2/20 0.33
PYGL P06737 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 1/20 0.33
PRNP P04156 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16110272 0.87 ABHD10 (0.44) TSHRMAPTGAALMNA
SCHEMBL14968329 0.85 HPGD (0.40) TSHRSMN1; SMN2
SCHEMBL9692301 0.84 HTT (0.45) TSHRHCAR3HCAR2MAPTHTT
SCHEMBL14967939 0.82 TSHR (0.48) TSHRHCAR3HCAR2GAAHTT
SCHEMBL14967432 0.81 ELANE (0.38) TSHRHCAR3HCAR2MAPTGAA
SCHEMBL14967326 0.80 ABCB1 (0.37) TSHRHCAR3HCAR2HTT
SCHEMBL14967754 0.80 LMNA (0.44) TSHRHCAR3HCAR2GAASMN1; SMN2
SCHEMBL28585875 0.80 HCAR3 (0.43) TSHRHCAR3HCAR2LMNA
SCHEMBL14968071 0.79 TSHR (0.40) TSHRPDCD1CD274MAPTGAA
SCHEMBL14967321 0.79 FABP7 (0.38) TSHRHCAR3HCAR2GAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed